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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
5 o9 U u: n. M8 s如果是中国长大的,英语能到这种程度真是很不简单。& [7 v$ d/ z2 Y" u; l
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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+ j. H. C. g) m9 X8 [8 gIt is a shame to see Nature — which nearly all scientists, including myself
, i. i8 U, r# X; V, regard as one of the most prestigious and influential physical-science, z( z' _2 q4 f6 b8 k
magazines — publish a thinly veiled biased article like this. Granted, this, u0 A* {5 X7 t$ j1 f% m, {, f4 c
is not a peer-reviewed scientific article and did not go through the4 @0 M A) s, y" r
scrutiny of picking referees. But to serve as a channel for the general2 R8 @5 t& A. \! v* t, a
populace to be in touch with and appreciate science, the authors and editors2 S! ]9 w; z* I0 R
should at least present the readers with facts within the proper context,$ i8 a$ v% B3 H( S R1 n) M
which they blatantly failed to do.( K S' k0 D3 u, t( c, K
+ E& U2 [' I2 n! Q6 z$ o& S( LFirst, to identify Ye’s performance increase, Ewen Callaway compared her+ u( F2 ^$ c& R: e
Olympic 400-metre IM time with her performance at the World Championships in
9 T2 T1 O- y" n& h) j2 B o# F. ?2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “ S' l) N) L8 N! v/ k2 d3 ]
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
0 C9 }: N0 Z, `# a- n0 J5 \" l) }personal best was 4:33.79 at the Asian Games in 2010. This leads to an
. v4 b+ m5 E7 n3 q8 cimprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the
& t. ~+ e" ?# n; W/ [4 P2 {difference between the gold and silver medal, I see no reason for 5.38 s to, i9 u1 k' f1 I4 b4 B
be treated as 7 s.5 p/ ]8 f0 X- e2 r
# a! f7 R. H$ e& ASecond, as previously pointed out, Ye is only 16 years old and her body is) T \* ~/ P' C& A' ?
still developing. Bettering oneself by 5 seconds over two years may seem- Q" j, d' x" Q% n) f
impossible for an adult swimmer, but it certainly happens among youngsters.8 J, R- {; F! e1 w( p8 `
An interview with Australian gold medallist Ian Thorpe revealed that his 4009 @) U, J; o5 u2 X! \
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.: @+ g; _5 a' _: L" \3 e# v
For regular people, including Callaway, it may be hard to imagine what an
2 f' _; Y, v, c$ F; ?) F) p, pelite swimmer can achieve as he or she matures and undergoes scientific and1 H5 Z- ?3 X j+ i
persistent training. But jumping to the conclusion that it is “anomalous”9 g _* x* u1 Q, ]0 `3 N
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.' ~- J, ~5 {6 L7 V3 O
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
- `3 x. [* Z6 d' V& aexample of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in/ j9 k9 _- L+ W: _
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so
; j K m% ]. d2 u( q: x3 dhe chose not to push himself too hard and to conserve his energy for later
2 f' Z p' H. ievents (whether this conforms to the Olympic spirit and the ‘use one’s0 y! g+ y ] F2 g- E$ P
best efforts to win a match’ requirement that the Badminton World
5 C% Q% l" l# IFederation recently invoked to disqualify four badminton pairs is another, i5 b' v4 ~: J. j( X. c0 m7 l4 i
topic worth discussing, though probably not in Nature). Ye, on the other
6 b0 d/ T" _% K) l2 r+ N% ?hand, was trailing behind after the first 300 metres and relied on freestyle# g, F$ y4 }, V& q
, in which she has an edge, to win the race. Failing to mention this
" }/ i! `3 G. J) {" dstrategic difference, as well as the fact that Lochte is 23.25 seconds9 c6 d9 B9 t' G% }' F
faster (4:05.18) than Ye overall, creates the illusion that a woman swam7 S t: G7 m% Q3 P
faster than the best man in the same sport, which sounds impossible. Putting
& n: i" H7 \0 L+ j) v' D. b! ^3 K8 Z# Naside the gender argument, I believe this is still a leading question that9 T( w v: |+ o% H- v% Q; G
implies to the reader that there is something fishy going on.0 T1 i/ i9 D4 E) y1 A0 ^
2 s. V# U" d/ w% b- ^" wFourth is another example of cherry-picking. In the same event, there are
" m) b9 k! [# n# L: q8 }four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.933 O: }2 p* M$ `
s) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s
. j; m3 _6 K& e4 t8 D( \8 ~), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
/ b# s) P# f% H" K& ]6 Mout, if we are just talking about the last 50 metres in a 400-metre IM,/ N" T* h/ [% M6 X( X) m( r2 o
Lochter is not the example I would have used if I were the author. What kind z/ w$ d: ^, H! V% c
of scientific rigorousness is Callaway trying to demonstrate here? Is it0 x0 j) `: P- H& L) p4 W
logical that if Lochter is the champion, we should assume that he leads in9 |4 L- b W9 r
every split? That would be a terrible way to teach the public how science! C8 f; u K; ], S1 v
works.
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and
% B ?0 L! w) u1 K7 Iimplies that a drug test cannot rule out the possibility of doping. Is this
6 A& M! {1 w3 f9 _& }kind of agnosticism what Nature really wants to teach its readers? By that
! U# j4 N% ^1 @& m4 f9 |/ Lstandard, I estimate that at least half of the peer-reviewed scientific
* e: g7 q0 J L: |papers in Nature should be retracted. How can one convince the editors and
1 e/ a/ K* J- }# a5 _& P2 S' |% }reviewers that their proposed theory works for every possible case? One% F' M }+ b2 t d* c, u$ k
cannot. One chooses to apply the theory to typical examples and to
# z# T' ^0 X7 c5 Tdemonstrate that in (hopefully) all scenarios considered, the theory works! J8 J: t4 y( F1 U# z8 q4 j
to a degree, and that that should warrant publication until a counterexample
7 f; `" p, W$ Q7 Q. s9 Ois found. I could imagine that Callaway has a sceptical mind, which is4 F& U9 G9 F H' U
crucial to scientific thinking, but that would be put to better use if he
% V' r! A9 k; nwrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
/ a$ p' ~- Z$ ~5 a9 z7 O ?$ Cadvanced, non-detectable drug that the Chinese have come up with in the
. A: }3 \& i3 [9 M& ~4 M. ppast 4 years (they obviously did not have it in Beijing, otherwise why not
2 P) w1 S& O2 Z! k9 ]use it and woo the audience at home?), based on data and rational derivation
x/ J% u: y4 D( \) C. This article, however, can be interpreted as saying that all athletes are
' y& k# L% f5 |# I ddoping and the authorities are just not good enough to catch them. That may! m" ?1 p6 m, Y! U
be true, logically, but definitely will not make the case if there is ever a3 W/ n0 `/ ]( |2 u
hearing by the governing body for water sports, FINA, to determine if Ye
& {' v: p$ q, Y) w/ O% k4 C; {$ Q5 ^0 zhas doped. To ask whether it is possible to obtain a false negative in a6 L4 [. r8 }! |) {% Z2 ^
drug test looks like a rigged question to me. Of course it is possible:4 G& N/ q$ M; n3 t: r t
other than the athlete taking a drug that the test is not designed to detect) V( a6 ^# ]1 g/ j
, anyone who has taken quantum 101 will tell you that everything is
2 D$ Z* E/ ?$ ]4 r0 h* vprobabilistic in nature, and so there is a probability that the drug in an
; M5 H+ O- G0 e ?4 p* ~+ ^athlete’s system could tunnel out right at the moment of the test. A slight
* p; x. ?( _% O D' `7 K& Y7 ochance it may be, but should we disregard all test results because of it?
6 y; s* f& p2 {0 _/ MLet’s be practical and reasonable, and accept that the World Anti-Doping
0 v' k3 p) \; v/ Iagency (WADA) is competent at its job. Ye’s urine sample will be stored for
8 i2 _! b7 |- J% w. w3 f# z+ ?eight years after the contest for future testing as technology advances.
6 F4 H( n& E5 B; A S, HInnocent until proven guilty, shouldn’t it be?# r% h* O2 ~1 q# ^, m; o
' b& R; O7 `- {Sixth, and the last point I would like to make, is that the out-of-0 Q! N1 r+ S' N& t$ E; `, m0 r
competition drug test is already in effect, which Callaway failed to mention/ K$ G# _8 [( c" c
. As noted in the president of WADA’s press release, drug testing for
' g3 N/ Q# n3 g% W! Y1 d3 NOlympians began at least six months before the opening of the London) F0 V( {. c/ I, w7 r/ k' G R- C) ~
Olympics. Furthermore, 107 athletes have been banned from this Olympics for( f/ L- T) m9 e+ h; D
doping. That may be the reason that “everyone will pass at the Olympic m% G7 ^3 J' f- N
games. Hardly anyone fails in competition testing” — those who did dope8 F# ]+ _ H+ d& |8 Q8 j6 x
have already been caught and sanctioned. Callaway is free to suggest that a, a7 \4 ~4 |, d# W* k+ h1 P T" a
player could have doped beforehand and fooled the test at the game, but this3 v6 y* N3 r* [8 A7 `# m$ v
possibility is certainly ruled out for Ye.
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2 h- m* U: \; f1 o# LOver all, even though Callaway did not falsify any data, he did (% Y7 N: F. d! s5 Z9 Q i+ b; H' n
intentionally or not) cherry-pick data that, in my view, are far too: f7 W3 f- A3 K* v4 o9 K$ H' z
suggestive to be fair and unbiased. If you want to cover a story of a
/ q' J/ N( m7 lsuspected doping from a scientific point of view, be impartial and provide
9 ~4 D7 \. |- B7 ^all the facts for the reader to judge. You are entitled to your9 A1 R. E' ?2 x) b5 p
interpretation of the facts, and the expression thereof in your piece,' ^4 c4 q l: ~- x3 F4 n8 u
explicitly or otherwise, but showing only evidence that favours your$ J# `* v* h" t( H% A& L
argument is hardly good science or journalism. Such an article in a journal. ^& y" N$ w1 ]1 v! X2 d1 u
such as Nature is not an appropriate example of how scientific research or
/ x6 A# C9 _ V+ E& s# Yreporting should be done. |
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