Postdoctoral position in single molecule biophysics

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Postdoctoral fellow
* X  d& Y  F+ rUniversity of Alberta and National Institute for Nanotechnology
% }0 n5 F8 |6 r5 k9 n3 }* TEdmonton, Alberta, Canada
2 b" Z+ |. w  U) P5 {Job ID: 6926659
Job Duration: 1-2 Years
8 I$ t( d( p1 h2 P# CPosition Title: Postdoctoral fellow
5 @: @+ _0 R+ ERequired Travel: None
Min Education: Ph.D.
Posted: June 23, 2010
Job Function: Postdoc
2 F+ x6 U7 P1 q  Q5 IMin Experience: None
Job Type: Full-Time
" P& {$ {" o: p: R2 T5 BSalary: Yearly Salary)


1 @/ ?5 z5 }- P" W) K  V  dPostdoctoral position in single molecule biophysics: protein folding and aggregation studies
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" J1 S* Y4 A) ^; C8 IA postdoctoral position in single-molecule biophysics is available immediately at the Department of Physics, University of Alberta and the National Institute for Nanotechnology, in the research group of Michael Woodside. A talented experimentalist is sought to conduct research into protein folding, misfolding, and aggregation, primarily using single-molecule fluorescence techniques. The successful candidates will work with a team of technicians and other researchers (at the University, the Institute, and in industry) to characterize the folding and aggregation behaviour of various disease-related proteins and to explore the effects of potential drugs on the folding/misfolding. These studies will be done using fluorescence spectroscopies (e.g. FCS and FRET), optical tweezers, and standard biochemical approaches. Responsibilities will include designing experiments; operating, maintaining, and improving instrumentation (as needed); analyzing data and writing papers; and working with other team members to translate experimental results into methods for studying drug candidates.
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5 p' p" c* \6 y% `( tThe National Institute for Nanotechnology is Canada’s flagship research institute in nanotechnology. It is located on the campus of the University of Alberta, in the provincial capital, Edmonton. A city of 1 million people, Edmonton has a lively cultural scene, and it also offers numerous opportunities for outdoors enthusiasts, especially in the unrivalled beauty of nearby Jasper and Banff national parks.

, w1 t# j* ~+ k# WTo apply, send a cover letter, curriculum vitae, and contact information (names, positions, phone numbers, mail and email addresses) for three references to Michael Woodside at michael.woodside@nrc-cnrc.gc.ca.
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Job Requirements

6 S+ Z+ d6 J8 m  zMotivated candidates with an interest in interdisciplinary research should have received a Ph.D. in physics, chemistry, biochemistry, biology or a closely related field within the last 2-3 years. Candidates should demonstrate a strong experimental record, with experience in single-molecule biophysics, fluorescence spectroscopy, force spectroscopy, laser optics, or protein folding, and should have a desire to learn and apply new techniques. Prior experience with single-molecule fluorescence methods would be particularly valued. Experience in molecular biology is helpful but not required, as technical support will be available in a fully-equipped biochemistry lab. The position is expected to last for at least 2 years.

Contact Person: Michael Woodside
Email Address: michael.woodside@nrc-cnrc.gc.ca
Phone: 780-641-1695

Employment Opportunity / City of Edmonton Community Services
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