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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG2 k3 u+ D w4 O! X! I3 X
如果是中国长大的,英语能到这种程度真是很不简单。! x; ?2 |8 w) P( c
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html( i" t, j H2 n! \
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania" G/ k% Q( Y* a6 e, L* M4 x& F
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It is a shame to see Nature — which nearly all scientists, including myself
$ M5 [' h: s u3 \, regard as one of the most prestigious and influential physical-science
8 G* m) u9 H% D6 b$ I9 T, n% X3 Kmagazines — publish a thinly veiled biased article like this. Granted, this$ H; V$ N/ s4 \* D' L8 {# l
is not a peer-reviewed scientific article and did not go through the
0 V9 y$ J; r) {/ g* S' \scrutiny of picking referees. But to serve as a channel for the general
: j9 S1 L: s0 i. `populace to be in touch with and appreciate science, the authors and editors
' G6 H: o4 d/ L1 jshould at least present the readers with facts within the proper context,! m/ y* P0 w, p' _; i( a$ V/ P: I3 d
which they blatantly failed to do.
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First, to identify Ye’s performance increase, Ewen Callaway compared her
& W8 L8 V E6 g/ c9 N rOlympic 400-metre IM time with her performance at the World Championships in! M' ^* [ p& v" r3 e- G
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
$ r* O3 E; ~ L) i5 Kanomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
1 Q9 R! h& V% j# upersonal best was 4:33.79 at the Asian Games in 2010. This leads to an
# p7 I' l5 R" M& Oimprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the
. ?) a2 x- C2 c% F, I0 Qdifference between the gold and silver medal, I see no reason for 5.38 s to
; W4 X( |$ P0 S6 @2 Tbe treated as 7 s.
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Second, as previously pointed out, Ye is only 16 years old and her body is
1 ^0 B F5 h( w+ Hstill developing. Bettering oneself by 5 seconds over two years may seem
4 h* J$ N5 G; x" g9 E% T/ Wimpossible for an adult swimmer, but it certainly happens among youngsters.( W! W" _% C, V
An interview with Australian gold medallist Ian Thorpe revealed that his 400# M, `- E# o6 ]+ t1 h
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.8 h0 A) X" I0 s
For regular people, including Callaway, it may be hard to imagine what an
) e3 z( A$ V( a% R/ relite swimmer can achieve as he or she matures and undergoes scientific and
1 C) m, d- r% c/ t- ?: h1 p1 @persistent training. But jumping to the conclusion that it is “anomalous”
& m ~) N' L6 O2 xbased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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- P! P) d! k; p9 JThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook6 G1 f& W7 q+ B+ V5 \4 L) @
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
' l. a( M w. O" N8 q) q6 Jthe last 50 metres, but Lochte had a huge lead in the first 300 metres, so
. P# Z+ R) q0 u b9 ehe chose not to push himself too hard and to conserve his energy for later% `) r3 i5 V% @: j4 {$ j- E' N
events (whether this conforms to the Olympic spirit and the ‘use one’s
" |" e; I# z% h- E' Bbest efforts to win a match’ requirement that the Badminton World
1 u" }# `* X* w: m4 WFederation recently invoked to disqualify four badminton pairs is another
8 @5 Z B# v8 V5 G% Z( Rtopic worth discussing, though probably not in Nature). Ye, on the other
6 C* ]5 K- A5 q* k3 ^hand, was trailing behind after the first 300 metres and relied on freestyle) M# }3 M6 P# F6 ?3 O
, in which she has an edge, to win the race. Failing to mention this
& J; F3 K- I: C' A. Cstrategic difference, as well as the fact that Lochte is 23.25 seconds3 ?' o2 ~ Y! P) _$ e4 ^; e, ^$ @$ B: m
faster (4:05.18) than Ye overall, creates the illusion that a woman swam
* f+ v7 D8 P# ]2 D9 ?faster than the best man in the same sport, which sounds impossible. Putting
1 `3 `% r! \' waside the gender argument, I believe this is still a leading question that
% a' h& a2 r' f5 Z$ F: ~implies to the reader that there is something fishy going on.; C {- v5 x0 ?3 T2 X
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Fourth is another example of cherry-picking. In the same event, there are, R7 Z$ V; [1 j* o& i
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
M4 q% Q' R' i# E- l0 U' X% Ns) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s& `- ^1 j8 K6 E5 v& d
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns7 ^" R1 o* O' D% k
out, if we are just talking about the last 50 metres in a 400-metre IM,& g+ b( ^# @8 t* _' _/ `- ^4 W
Lochter is not the example I would have used if I were the author. What kind
$ _0 p' `! [) G5 O" tof scientific rigorousness is Callaway trying to demonstrate here? Is it
1 V( ^9 g5 o3 ^, l, rlogical that if Lochter is the champion, we should assume that he leads in* k s: f* G# i" x8 @& I5 S. D. E
every split? That would be a terrible way to teach the public how science
# G, E5 ?5 `8 T( Gworks.+ {* m7 ^7 z% u# K& I: L C4 p8 r- j
9 w% } x& K2 G% i3 c5 g/ y1 LFifth is the issue I oppose the most. Callaway quotes Ross Tucker and! H- C4 a! u7 S! y) L# Z
implies that a drug test cannot rule out the possibility of doping. Is this
+ e2 c' t" @+ Y% o3 G* A Akind of agnosticism what Nature really wants to teach its readers? By that# K0 ^0 B. e' O; L0 R+ I7 w
standard, I estimate that at least half of the peer-reviewed scientific. I4 w5 P1 p. x! ^$ i- C
papers in Nature should be retracted. How can one convince the editors and8 }# ^$ [9 l l+ \! ?
reviewers that their proposed theory works for every possible case? One2 u; F) S3 o G+ \+ G
cannot. One chooses to apply the theory to typical examples and to
; _5 i1 z6 ~+ s+ l# Y, @; Z3 D/ a5 mdemonstrate that in (hopefully) all scenarios considered, the theory works
& k# L c% v! ^% B" Z4 Mto a degree, and that that should warrant publication until a counterexample
; D# m# }2 l/ c$ E7 n) r6 Xis found. I could imagine that Callaway has a sceptical mind, which is+ Z" E; B6 h. [4 n
crucial to scientific thinking, but that would be put to better use if he
8 J. T% F! f" ]" {wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
1 O' t4 a" x$ o. q7 o% o7 k7 hadvanced, non-detectable drug that the Chinese have come up with in the
8 x+ u' T' I2 r- Vpast 4 years (they obviously did not have it in Beijing, otherwise why not
! w y8 l/ L! Y3 u0 J+ Zuse it and woo the audience at home?), based on data and rational derivation
+ e' l% I8 E5 t. This article, however, can be interpreted as saying that all athletes are2 u8 x" Y& q! L }/ Z5 u: H
doping and the authorities are just not good enough to catch them. That may& j) Q6 y4 M0 l- G# ]- M/ ]
be true, logically, but definitely will not make the case if there is ever a
; G$ h( n! S; N1 B3 e, l5 o9 vhearing by the governing body for water sports, FINA, to determine if Ye
: L) R; e V' c4 S0 u+ j4 k" s; m( Mhas doped. To ask whether it is possible to obtain a false negative in a
" g% o% ], }3 r U% Adrug test looks like a rigged question to me. Of course it is possible:
$ | |+ }2 R* bother than the athlete taking a drug that the test is not designed to detect: P" {% B# j* n% W6 e/ D
, anyone who has taken quantum 101 will tell you that everything is. }3 |( f3 u' q. X
probabilistic in nature, and so there is a probability that the drug in an
* c: i- X9 X8 ]4 p9 Bathlete’s system could tunnel out right at the moment of the test. A slight, {0 ~; @0 m- e2 y) b
chance it may be, but should we disregard all test results because of it?
, D$ t& ~* X% ~4 P/ GLet’s be practical and reasonable, and accept that the World Anti-Doping
0 e2 G+ M* G1 v5 \# f; fagency (WADA) is competent at its job. Ye’s urine sample will be stored for
: W& y# @; n4 P* U9 q* m( Ueight years after the contest for future testing as technology advances.
) L( |( U2 G9 o$ ^: CInnocent until proven guilty, shouldn’t it be?7 C3 `; V, o+ B& T1 V1 d$ y
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Sixth, and the last point I would like to make, is that the out-of-. n, N( ~1 G9 ~
competition drug test is already in effect, which Callaway failed to mention
" ~1 i+ p0 V0 H3 o7 u7 Z& M h1 I. As noted in the president of WADA’s press release, drug testing for
8 k! u3 h3 t4 G% HOlympians began at least six months before the opening of the London
2 w1 ?7 W4 b$ J- m( S& ROlympics. Furthermore, 107 athletes have been banned from this Olympics for
; R, c1 L' U& udoping. That may be the reason that “everyone will pass at the Olympic
, c' @, R$ t2 ygames. Hardly anyone fails in competition testing” — those who did dope
) r5 N; g0 m8 n+ r7 j. D" Uhave already been caught and sanctioned. Callaway is free to suggest that a
, J3 `* t# w. O( V2 S% lplayer could have doped beforehand and fooled the test at the game, but this
. W. x+ G! O/ Lpossibility is certainly ruled out for Ye.9 A8 J$ n4 P, P/ J$ h7 d
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Over all, even though Callaway did not falsify any data, he did (
0 c" M$ D7 w# A, gintentionally or not) cherry-pick data that, in my view, are far too* V4 B8 a+ U& p( R; v; r9 F
suggestive to be fair and unbiased. If you want to cover a story of a
9 J5 K. f* O+ w3 J) \* Lsuspected doping from a scientific point of view, be impartial and provide
+ y Z6 {/ g$ i& T. ]all the facts for the reader to judge. You are entitled to your
- q0 O' X6 o4 `+ I8 ninterpretation of the facts, and the expression thereof in your piece,4 _: m# D8 N# n- C" x, q1 c) d, L
explicitly or otherwise, but showing only evidence that favours your
% C1 p& ~# D( rargument is hardly good science or journalism. Such an article in a journal2 k6 g1 j/ y$ p( j
such as Nature is not an appropriate example of how scientific research or
% Y( m* ~9 h) t8 K; {6 Ureporting should be done. |
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