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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
+ t" B p7 b$ P% u如果是中国长大的,英语能到这种程度真是很不简单。, k4 y6 i u( S I
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html. R) [: K" d- g& |
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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It is a shame to see Nature — which nearly all scientists, including myself
/ ~- ?9 D) o7 A, regard as one of the most prestigious and influential physical-science
, g: [) W7 {4 nmagazines — publish a thinly veiled biased article like this. Granted, this
8 c! p' x$ I5 [is not a peer-reviewed scientific article and did not go through the2 z& x4 n8 @/ N: e
scrutiny of picking referees. But to serve as a channel for the general5 x6 ]1 B8 O0 d- ^6 Q# C
populace to be in touch with and appreciate science, the authors and editors
5 R6 t2 m# F) v" A b& R+ |should at least present the readers with facts within the proper context,) \; S- B$ g, Z) A9 t. A) J: }
which they blatantly failed to do.
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! t, G0 e* P8 wFirst, to identify Ye’s performance increase, Ewen Callaway compared her1 R- U0 K' \7 ~4 s
Olympic 400-metre IM time with her performance at the World Championships in
! \- Q6 \+ R% c8 M+ H% c2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
& d9 ~/ F/ o# v% Y" @anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous6 O) x# k1 Q% _ B5 Y& Z: V
personal best was 4:33.79 at the Asian Games in 2010. This leads to an
; p! H2 e4 i6 D: T. i) jimprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the3 N W4 R' w& _# d
difference between the gold and silver medal, I see no reason for 5.38 s to9 e2 n! C% x( q3 O5 H# g
be treated as 7 s.
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) _* Y5 i, o4 m* A, ]$ T. w( F1 rSecond, as previously pointed out, Ye is only 16 years old and her body is: N/ j! z4 }* |6 {1 q0 S2 o
still developing. Bettering oneself by 5 seconds over two years may seem
& H' h5 p$ _( v, h* `" eimpossible for an adult swimmer, but it certainly happens among youngsters.
! R# Y8 L- h$ t9 e! i4 j! i* r8 FAn interview with Australian gold medallist Ian Thorpe revealed that his 400" M: e9 m0 }- B4 G# k% d; u) D
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
1 G2 e3 m! x9 F4 t) ?For regular people, including Callaway, it may be hard to imagine what an3 w/ f$ ?* ?. E) q# A T
elite swimmer can achieve as he or she matures and undergoes scientific and
2 ]/ c! Q% n" z I/ jpersistent training. But jumping to the conclusion that it is “anomalous”
4 q3 B+ Z1 k+ Z% t9 i# W; }: A: O9 fbased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook2 b+ U" b$ ]6 O) ]) J4 k; c' Q
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in* C7 N E9 F. I( B
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so
/ @6 J$ h0 z! U" q- yhe chose not to push himself too hard and to conserve his energy for later# r. B, \. f: q: h4 T* W# n
events (whether this conforms to the Olympic spirit and the ‘use one’s
& R3 O! j/ C$ w' v! D( Jbest efforts to win a match’ requirement that the Badminton World
# Q% l$ L0 k( o) i, `7 KFederation recently invoked to disqualify four badminton pairs is another
3 ?6 f) n+ X0 |, X$ t4 btopic worth discussing, though probably not in Nature). Ye, on the other. T6 Z9 F& e- F+ O0 }$ w1 d- n
hand, was trailing behind after the first 300 metres and relied on freestyle
4 J; I: }+ z: s8 H, in which she has an edge, to win the race. Failing to mention this5 F" u0 K" t8 R* k% V) N
strategic difference, as well as the fact that Lochte is 23.25 seconds0 i4 z+ r9 r- g c
faster (4:05.18) than Ye overall, creates the illusion that a woman swam
7 a. R5 ?0 I( R) i- x7 R8 F5 ffaster than the best man in the same sport, which sounds impossible. Putting1 B/ ]% l2 [) H6 ~
aside the gender argument, I believe this is still a leading question that
5 F% n5 P9 C, s, M; U1 C eimplies to the reader that there is something fishy going on.
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Fourth is another example of cherry-picking. In the same event, there are3 t/ \4 z' d* z% u1 p
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
2 ^8 l! P) G, B7 L+ C$ Ns) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s6 v* K4 S5 F' ?( O1 X! V0 Y
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
. C: y/ A9 R( N; Zout, if we are just talking about the last 50 metres in a 400-metre IM,: H: o T* {. ? \3 x" @. f
Lochter is not the example I would have used if I were the author. What kind
+ j; y" A$ k$ }! i9 _! g" Tof scientific rigorousness is Callaway trying to demonstrate here? Is it1 g* y# h& E/ V' _1 \
logical that if Lochter is the champion, we should assume that he leads in
' E+ T; W& z; w3 F; Vevery split? That would be a terrible way to teach the public how science- [2 H" Z8 W, k" [ s5 j
works.
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and* U% E1 S; l( X5 h
implies that a drug test cannot rule out the possibility of doping. Is this
S0 W7 V; F) F) O+ Gkind of agnosticism what Nature really wants to teach its readers? By that( Y% B1 p# X. D# Z+ ?6 g- T' b
standard, I estimate that at least half of the peer-reviewed scientific
G% J3 o: X& w0 jpapers in Nature should be retracted. How can one convince the editors and
9 O6 r! E# }6 S" h9 u9 Y2 b9 l; Lreviewers that their proposed theory works for every possible case? One( A+ r% U. c' u2 j
cannot. One chooses to apply the theory to typical examples and to
" C5 D5 U! m* |. O/ Xdemonstrate that in (hopefully) all scenarios considered, the theory works
! q6 r. U% W9 V$ Fto a degree, and that that should warrant publication until a counterexample7 l& k$ z: {: N" M m# h# F3 \
is found. I could imagine that Callaway has a sceptical mind, which is- \0 Z' R2 b# g
crucial to scientific thinking, but that would be put to better use if he8 u6 ]: `9 H( S. h1 o& E5 u
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
( n- m) [* ]( a% i4 Qadvanced, non-detectable drug that the Chinese have come up with in the
- q" `, v: D$ ?5 s1 {2 h+ F, Xpast 4 years (they obviously did not have it in Beijing, otherwise why not3 M0 Z4 A+ J# O. z9 c2 x( e
use it and woo the audience at home?), based on data and rational derivation
9 c3 Z6 f$ w$ B, ]& N. This article, however, can be interpreted as saying that all athletes are; c6 V9 C& R/ p6 F! P% D/ w
doping and the authorities are just not good enough to catch them. That may4 r) ?' \+ G* S
be true, logically, but definitely will not make the case if there is ever a
. d( ?, `; i" P6 e1 ?hearing by the governing body for water sports, FINA, to determine if Ye( ?4 K- w. A: O1 b/ B4 |: Y* ]" ^
has doped. To ask whether it is possible to obtain a false negative in a
' i9 E. `7 k' v! {' Odrug test looks like a rigged question to me. Of course it is possible:5 x9 _6 O# b* p m
other than the athlete taking a drug that the test is not designed to detect
( T Y. B7 J& ^, _, anyone who has taken quantum 101 will tell you that everything is
1 d4 @% C- t$ U6 y; _4 n5 F/ Aprobabilistic in nature, and so there is a probability that the drug in an
( _# }* \4 T) A7 Cathlete’s system could tunnel out right at the moment of the test. A slight
6 Y+ J6 w r) {chance it may be, but should we disregard all test results because of it?
, S5 d/ U: W2 sLet’s be practical and reasonable, and accept that the World Anti-Doping2 d$ i9 A( p' h0 S1 |7 a9 b. I- y
agency (WADA) is competent at its job. Ye’s urine sample will be stored for. X3 k9 R6 g- C0 [! v) H& d
eight years after the contest for future testing as technology advances.7 p5 C6 u; g4 }- M2 y0 Q2 l+ ]
Innocent until proven guilty, shouldn’t it be?
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Sixth, and the last point I would like to make, is that the out-of-
; G6 K" s3 q- }, ~3 D* {8 Xcompetition drug test is already in effect, which Callaway failed to mention
8 O. q1 A- a! o! Z* m. As noted in the president of WADA’s press release, drug testing for
( g9 D+ p: \" z8 Q" POlympians began at least six months before the opening of the London {! K) k* F" O' e% ~+ C$ P$ {( X/ ^
Olympics. Furthermore, 107 athletes have been banned from this Olympics for
# ]7 V9 H# t3 t4 N9 hdoping. That may be the reason that “everyone will pass at the Olympic
( z! e; q0 t3 ]. e! q# b6 q1 V6 \games. Hardly anyone fails in competition testing” — those who did dope; U! ^4 M! \# E
have already been caught and sanctioned. Callaway is free to suggest that a
( O( P2 m2 N' A: Z# Fplayer could have doped beforehand and fooled the test at the game, but this
( g5 K& K9 M4 ?8 O/ ?+ Vpossibility is certainly ruled out for Ye.
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Over all, even though Callaway did not falsify any data, he did (8 c: j6 |9 W( F6 f
intentionally or not) cherry-pick data that, in my view, are far too7 H- l- P# n m0 m
suggestive to be fair and unbiased. If you want to cover a story of a
$ @# _5 E& _2 x' |! ysuspected doping from a scientific point of view, be impartial and provide; f! z- Y, [2 I ?6 x: P4 A
all the facts for the reader to judge. You are entitled to your9 b; l. m6 V n% z
interpretation of the facts, and the expression thereof in your piece,
7 i' N7 \% p+ W: V' jexplicitly or otherwise, but showing only evidence that favours your. b" B K- F/ Q
argument is hardly good science or journalism. Such an article in a journal
* G8 B6 b/ k& e3 p3 v8 H3 T5 Gsuch as Nature is not an appropriate example of how scientific research or
/ v' b9 K, o: Z D" y4 C5 G3 |reporting should be done. |
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