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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG( l0 ]1 p, s% U g9 [
如果是中国长大的,英语能到这种程度真是很不简单。
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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It is a shame to see Nature — which nearly all scientists, including myself
2 h4 e) c1 u& d) b' q7 A8 o5 f* o, regard as one of the most prestigious and influential physical-science
1 s" w2 H- x+ n. kmagazines — publish a thinly veiled biased article like this. Granted, this7 K1 Y4 D; B! w
is not a peer-reviewed scientific article and did not go through the% ]; I9 r, ?" D$ c8 T a/ `
scrutiny of picking referees. But to serve as a channel for the general
. o5 B$ @" E& ~3 Q3 Bpopulace to be in touch with and appreciate science, the authors and editors& _3 n. l$ r0 }0 z, b# y) Q2 x
should at least present the readers with facts within the proper context,
2 }: o( t$ H: S m5 n# S1 bwhich they blatantly failed to do.
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First, to identify Ye’s performance increase, Ewen Callaway compared her' w) i2 }* S3 i4 _/ t5 p/ E ~
Olympic 400-metre IM time with her performance at the World Championships in1 L! F6 J: u2 |, M$ L6 o& E
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
: d% f! O- p- S7 y% I8 Y% banomalous” improvement of around 7 seconds (6.72 s). In fact, her previous! V( w& Y9 ?6 r- w: f; j0 t% h
personal best was 4:33.79 at the Asian Games in 2010. This leads to an
+ s6 M" I9 U3 V/ Limprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the
# x o2 M% r; z* q- j; C5 w, rdifference between the gold and silver medal, I see no reason for 5.38 s to# s1 v2 T1 Q9 \9 t# R; e3 C
be treated as 7 s.; n0 r: t0 g. X! z, [9 L
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Second, as previously pointed out, Ye is only 16 years old and her body is
4 Q# m* X3 u4 }still developing. Bettering oneself by 5 seconds over two years may seem/ O* N# i! w4 I: s
impossible for an adult swimmer, but it certainly happens among youngsters.
4 Y* d# p5 p, m! A4 k. |An interview with Australian gold medallist Ian Thorpe revealed that his 400/ \. B4 e6 I, ?& U1 Q# n! N
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.6 @+ L1 A! \7 a5 g9 V; [
For regular people, including Callaway, it may be hard to imagine what an; d0 T% E0 T1 f1 ^' l& C" R
elite swimmer can achieve as he or she matures and undergoes scientific and0 s* G) S) d; w$ D0 j: \( y! P/ q4 t
persistent training. But jumping to the conclusion that it is “anomalous”$ x& ^9 p; c1 l8 @; z
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.& e2 o8 W( l! N0 `) F* G: N! U
8 r6 L! W# N1 ~+ i' q2 f. Y9 jThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook$ T- ^" f; e1 E$ I3 t# z( y
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
- ~/ I; }/ `: l: F' q" Vthe last 50 metres, but Lochte had a huge lead in the first 300 metres, so
9 q: X3 I, Z& k0 s+ }7 E8 X/ u, ?he chose not to push himself too hard and to conserve his energy for later2 X: @% g4 Q$ v
events (whether this conforms to the Olympic spirit and the ‘use one’s7 N2 Z1 n( X" r( }7 k* E9 ^* A
best efforts to win a match’ requirement that the Badminton World
6 s x1 n/ V3 q/ {2 nFederation recently invoked to disqualify four badminton pairs is another$ ], @0 T! B' F( w; K
topic worth discussing, though probably not in Nature). Ye, on the other) v/ U1 P8 X- l9 M' ]8 B
hand, was trailing behind after the first 300 metres and relied on freestyle
E: l2 C7 e8 d, F W3 G; A, in which she has an edge, to win the race. Failing to mention this
6 k* t( ^8 }2 f) P$ `strategic difference, as well as the fact that Lochte is 23.25 seconds
! B; t7 { ]& g$ cfaster (4:05.18) than Ye overall, creates the illusion that a woman swam
+ V4 w# M( O# Y: gfaster than the best man in the same sport, which sounds impossible. Putting
4 a( q4 g8 J, S3 e4 x! F ^' yaside the gender argument, I believe this is still a leading question that% ?" i, O: {0 B1 B' t& h: a
implies to the reader that there is something fishy going on.8 {2 D. e% y5 [9 K6 R' p$ b& \6 E
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Fourth is another example of cherry-picking. In the same event, there are/ Z5 X( ]4 ?/ y( Z$ H
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
5 M M0 b/ o" r# l+ f8 l: Ys) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s
' U0 i- A$ g0 B1 G, d* k! W), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns/ n5 q" C v9 h2 x9 m$ L
out, if we are just talking about the last 50 metres in a 400-metre IM,5 B! C2 }- _0 J6 A
Lochter is not the example I would have used if I were the author. What kind: W- s/ f( _: x# F; P4 ~& w6 r
of scientific rigorousness is Callaway trying to demonstrate here? Is it3 i1 n+ L/ X5 T' q' v
logical that if Lochter is the champion, we should assume that he leads in
v) U- V% I7 |/ Kevery split? That would be a terrible way to teach the public how science
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and O! v' Y8 ` r, h1 Q
implies that a drug test cannot rule out the possibility of doping. Is this2 I- E; \+ ~& w! i4 K
kind of agnosticism what Nature really wants to teach its readers? By that0 J5 B) e' D4 ^3 r% h
standard, I estimate that at least half of the peer-reviewed scientific9 E$ p* r$ @# q
papers in Nature should be retracted. How can one convince the editors and
5 q) j% m0 u$ dreviewers that their proposed theory works for every possible case? One
% h$ C- O& a; b7 A% U$ ?cannot. One chooses to apply the theory to typical examples and to
1 D( ]4 b8 M1 f1 o5 |) X' Qdemonstrate that in (hopefully) all scenarios considered, the theory works: u' d! B1 z! c& Z
to a degree, and that that should warrant publication until a counterexample
, M* E7 `# s$ L" qis found. I could imagine that Callaway has a sceptical mind, which is
9 N# B& w+ v9 mcrucial to scientific thinking, but that would be put to better use if he& M4 R3 V) c& a
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
' r( n+ l/ i" p& @advanced, non-detectable drug that the Chinese have come up with in the
0 ]% K3 I7 k, [- `+ h% R4 W9 Npast 4 years (they obviously did not have it in Beijing, otherwise why not- j. \8 i' s. d ]7 c% j3 i
use it and woo the audience at home?), based on data and rational derivation% w0 ? {& }: o% I. |' I
. This article, however, can be interpreted as saying that all athletes are& A) u5 G; N0 G7 v
doping and the authorities are just not good enough to catch them. That may$ F0 V L. S. m! }
be true, logically, but definitely will not make the case if there is ever a
^# n* z5 ?" ?hearing by the governing body for water sports, FINA, to determine if Ye/ g/ @7 \$ F) P( S5 g
has doped. To ask whether it is possible to obtain a false negative in a% b% R3 \; \9 h8 A
drug test looks like a rigged question to me. Of course it is possible:
' K9 E: \+ m0 Sother than the athlete taking a drug that the test is not designed to detect) W7 l7 F$ u% t. z$ q8 P' t h* [
, anyone who has taken quantum 101 will tell you that everything is
2 ^2 v$ L" p' U r8 }7 uprobabilistic in nature, and so there is a probability that the drug in an; N, H p/ R% y
athlete’s system could tunnel out right at the moment of the test. A slight" ^( }7 }4 o% q8 A6 g0 I& G
chance it may be, but should we disregard all test results because of it?" E% ^7 k3 w% r0 j+ b
Let’s be practical and reasonable, and accept that the World Anti-Doping' p( {8 J& Z' Z
agency (WADA) is competent at its job. Ye’s urine sample will be stored for
8 ]" R5 V2 n/ u" s2 H8 ]eight years after the contest for future testing as technology advances.; x6 d0 q n2 m' W [
Innocent until proven guilty, shouldn’t it be?2 r: S- d1 h1 W8 o, `3 f. |
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Sixth, and the last point I would like to make, is that the out-of-0 w& V0 u* |* ~
competition drug test is already in effect, which Callaway failed to mention
. C1 \7 k: @7 }1 z1 _, d. As noted in the president of WADA’s press release, drug testing for/ c8 P B' r" K5 c
Olympians began at least six months before the opening of the London
1 Q8 r7 h/ H6 h6 o: O1 cOlympics. Furthermore, 107 athletes have been banned from this Olympics for
" @% | q# W) Z! t# h% Z U0 Odoping. That may be the reason that “everyone will pass at the Olympic1 h+ u" {. R0 d& Q6 A7 F
games. Hardly anyone fails in competition testing” — those who did dope# [8 v' {# q% Y- @9 r/ o1 r' I+ n
have already been caught and sanctioned. Callaway is free to suggest that a
b# u/ `$ r/ @, T, C7 e1 T3 `player could have doped beforehand and fooled the test at the game, but this
" Z1 E! y" N! Mpossibility is certainly ruled out for Ye.( F& f: U% `- `" z
8 q" V* _- v6 K. n% v9 sOver all, even though Callaway did not falsify any data, he did (
6 x& E( e$ s9 e' ~; Q* M; ~) Z6 ^intentionally or not) cherry-pick data that, in my view, are far too
- I) w! G8 t7 {% isuggestive to be fair and unbiased. If you want to cover a story of a
& D$ p& H* }$ a7 B1 }suspected doping from a scientific point of view, be impartial and provide
6 `3 y" |" s8 K4 w- C2 Y. mall the facts for the reader to judge. You are entitled to your* o) I& Q! V$ I4 C: e9 I @, g$ B. s
interpretation of the facts, and the expression thereof in your piece,
4 Y9 [" L$ E) i( X3 A2 C# kexplicitly or otherwise, but showing only evidence that favours your* } Z! G& s p8 E1 x. D3 F
argument is hardly good science or journalism. Such an article in a journal3 t" `8 A( M% a" Q$ S
such as Nature is not an appropriate example of how scientific research or
! k8 h8 G( N2 ]reporting should be done. |
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