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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
# l' T$ V/ `& R! N: g( r1 @* c如果是中国长大的,英语能到这种程度真是很不简单。
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html* W L) n1 M: M
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania+ _4 D* ?* i( J# X- N* j' |$ U
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It is a shame to see Nature — which nearly all scientists, including myself- ~& m0 c$ Y; p7 e9 K0 E6 r( h
, regard as one of the most prestigious and influential physical-science8 \/ v/ w2 |( I2 E
magazines — publish a thinly veiled biased article like this. Granted, this
6 ]$ p" w! G2 ^& xis not a peer-reviewed scientific article and did not go through the
) }' j4 b' ~/ y4 p* ?9 jscrutiny of picking referees. But to serve as a channel for the general
- X0 `7 `. I% b( D* Fpopulace to be in touch with and appreciate science, the authors and editors
6 w1 C5 Q6 k* [should at least present the readers with facts within the proper context,$ \0 I! G+ H2 }* s0 D* }9 F
which they blatantly failed to do.* t6 A; U* y$ m- y2 s5 |
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First, to identify Ye’s performance increase, Ewen Callaway compared her
1 e+ r* i: o! ?2 z9 i5 UOlympic 400-metre IM time with her performance at the World Championships in
8 s5 }- M* v. ]: G2 v4 \2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
7 O+ {# a# y6 M/ L: Oanomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
( t/ ], O" C( b5 x6 [personal best was 4:33.79 at the Asian Games in 2010. This leads to an3 b! w8 o- p/ V& }4 b/ h
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
8 f* q: n/ S' S, M# o' `difference between the gold and silver medal, I see no reason for 5.38 s to
% G* a6 @. P" l. D7 zbe treated as 7 s.( v+ e0 Y1 y% m1 k6 L0 M; @. T
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Second, as previously pointed out, Ye is only 16 years old and her body is" S6 X: r) g7 s' ^; M; Z, i1 o7 o
still developing. Bettering oneself by 5 seconds over two years may seem1 r! m g) o6 u# P: q% V) u, ]
impossible for an adult swimmer, but it certainly happens among youngsters.5 Q ]0 w+ X- \! z1 |* r1 [) _0 }
An interview with Australian gold medallist Ian Thorpe revealed that his 400
( y3 h Q7 H/ O p) i: X-metre freestyle time improved by 5 seconds between the ages of 15 and 16.$ C5 U) ?& B+ S2 p. `; a# G
For regular people, including Callaway, it may be hard to imagine what an4 e$ |2 j7 g, S# p) @
elite swimmer can achieve as he or she matures and undergoes scientific and3 t/ X# |! J5 A
persistent training. But jumping to the conclusion that it is “anomalous”" m- T" F1 q4 N; d/ J8 W4 @! W
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook1 A" u& V8 C% O: v
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
% F8 p7 j" g* ^$ t* ~the last 50 metres, but Lochte had a huge lead in the first 300 metres, so
. G6 s: t3 ]7 m/ H* L% }" r+ Ehe chose not to push himself too hard and to conserve his energy for later
0 z4 t4 w, Z5 Y( {0 S# |events (whether this conforms to the Olympic spirit and the ‘use one’s
1 u) k+ `, ~: |# ^! y* M2 t3 F4 R1 vbest efforts to win a match’ requirement that the Badminton World, O7 _) n* l, \& D' x$ {
Federation recently invoked to disqualify four badminton pairs is another
8 G$ F9 o7 r6 G. Ftopic worth discussing, though probably not in Nature). Ye, on the other
# v4 M9 v6 K% E" Zhand, was trailing behind after the first 300 metres and relied on freestyle8 n4 ~; R7 N" o. o$ O+ h3 d
, in which she has an edge, to win the race. Failing to mention this
! g- T2 B: Y; Q! ^; X+ hstrategic difference, as well as the fact that Lochte is 23.25 seconds# U7 r1 Q7 [3 P7 ^1 }
faster (4:05.18) than Ye overall, creates the illusion that a woman swam
9 C" q! c7 o( {, M5 o% v3 xfaster than the best man in the same sport, which sounds impossible. Putting
% ^2 o* g) P) V& e$ A1 Naside the gender argument, I believe this is still a leading question that, b( W- v6 W$ L0 M7 G! A
implies to the reader that there is something fishy going on.) K7 M. `, t& m6 Y b8 Y
; ]- o1 R6 B/ y# AFourth is another example of cherry-picking. In the same event, there are
R) [0 F4 @/ O/ ]/ ]4 a, ^four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93. I6 F4 d7 C+ L Q" k+ o
s) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s
% e1 I: q2 V2 I) p% h# J3 W2 y* s; R), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
" g7 b5 f2 X3 s" o( `! Pout, if we are just talking about the last 50 metres in a 400-metre IM,
b+ b' f6 g6 y5 uLochter is not the example I would have used if I were the author. What kind
; ]$ g7 Z, X' v2 m4 p/ Qof scientific rigorousness is Callaway trying to demonstrate here? Is it
% @" `+ l& Z8 x: f0 T v5 Ulogical that if Lochter is the champion, we should assume that he leads in
, r3 j* }- T7 L3 R7 }1 o( Z1 Ievery split? That would be a terrible way to teach the public how science
0 v6 `7 t' M/ o9 iworks.. P* h0 k: b6 ]$ b: |6 R
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and# o) q% f# o N% x
implies that a drug test cannot rule out the possibility of doping. Is this
6 d) {: \( F7 h' n$ i1 j% R2 x) a7 Ekind of agnosticism what Nature really wants to teach its readers? By that& ]) L' ~& C' U
standard, I estimate that at least half of the peer-reviewed scientific
7 j$ |& S' h3 d1 u$ rpapers in Nature should be retracted. How can one convince the editors and
8 w4 E& ?* t; L- u. f3 a" Rreviewers that their proposed theory works for every possible case? One; f$ C) N8 r2 R# h% h h1 g; h
cannot. One chooses to apply the theory to typical examples and to1 A. l; ] ]. E- j7 ^; O& |1 S$ Q$ \
demonstrate that in (hopefully) all scenarios considered, the theory works9 y/ j+ s; u# [) {) _
to a degree, and that that should warrant publication until a counterexample$ b! A) o, l4 A4 w
is found. I could imagine that Callaway has a sceptical mind, which is6 n3 {5 p: K, d( {. N
crucial to scientific thinking, but that would be put to better use if he
2 ^5 D, I4 T* {$ J5 bwrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
" g0 ]6 e1 D6 Z) nadvanced, non-detectable drug that the Chinese have come up with in the& w3 M+ k/ v8 O2 |8 G+ D/ u( {
past 4 years (they obviously did not have it in Beijing, otherwise why not6 @. i/ ~/ ^# ~2 V0 l9 r& M. H H8 I
use it and woo the audience at home?), based on data and rational derivation
7 }" y& T+ B1 A, Q: ^* J. w. This article, however, can be interpreted as saying that all athletes are3 Q. D" K9 D( ]' m* R
doping and the authorities are just not good enough to catch them. That may
$ A! t0 k8 k4 tbe true, logically, but definitely will not make the case if there is ever a
4 J, L: A4 p/ x: O4 p: V- Khearing by the governing body for water sports, FINA, to determine if Ye% |) _2 c1 X3 t6 [# J6 [0 H: q( o
has doped. To ask whether it is possible to obtain a false negative in a* g7 ^( B0 L/ p% c, Z
drug test looks like a rigged question to me. Of course it is possible:; W: Q0 x* C' n" c: L: z, S
other than the athlete taking a drug that the test is not designed to detect! S: n2 P4 t3 T
, anyone who has taken quantum 101 will tell you that everything is
) x" u# g; U s: Kprobabilistic in nature, and so there is a probability that the drug in an) p% O2 }3 Z) A( F N" L
athlete’s system could tunnel out right at the moment of the test. A slight9 A1 \' u+ J! {" W0 n# C
chance it may be, but should we disregard all test results because of it?( F7 x+ P3 Q9 Y+ ?7 s. ^8 x; e
Let’s be practical and reasonable, and accept that the World Anti-Doping
' v' w1 |: ^; ?agency (WADA) is competent at its job. Ye’s urine sample will be stored for
0 p$ v4 T- o1 a2 Y1 X0 B) G! veight years after the contest for future testing as technology advances.
2 ]& E& I" { l8 n* \% S- v* [* QInnocent until proven guilty, shouldn’t it be?" v1 G+ A7 [9 k
% j$ O+ c! { \( ]% n1 RSixth, and the last point I would like to make, is that the out-of-+ X' y& U6 ^% j$ Y8 f7 a- P8 \% @
competition drug test is already in effect, which Callaway failed to mention
0 u- o8 U& V0 Z4 N! j" [, N. As noted in the president of WADA’s press release, drug testing for& X/ I p; U$ m+ \% g6 x; i
Olympians began at least six months before the opening of the London: J+ y2 }' ]- z, C7 [) r" @+ h
Olympics. Furthermore, 107 athletes have been banned from this Olympics for) x* L% U# t7 B, y" }
doping. That may be the reason that “everyone will pass at the Olympic6 ^6 l# g- W* b2 Z. i1 l
games. Hardly anyone fails in competition testing” — those who did dope; z7 W2 M W0 J8 s. P! J
have already been caught and sanctioned. Callaway is free to suggest that a9 [, F# @3 R- C( x
player could have doped beforehand and fooled the test at the game, but this* v* j& S1 p6 Q* N
possibility is certainly ruled out for Ye.
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Over all, even though Callaway did not falsify any data, he did (
$ {# U( z4 A% s% g: ^ bintentionally or not) cherry-pick data that, in my view, are far too
0 D& J% l% z/ T9 u& \) b' |suggestive to be fair and unbiased. If you want to cover a story of a( O! n. Z! B% h0 _/ t' U( g6 ^& u( F
suspected doping from a scientific point of view, be impartial and provide: y+ q: `' ]7 C/ z) O' I0 ?4 w
all the facts for the reader to judge. You are entitled to your
7 D. P9 b% @$ h1 P; n8 L% U* N" Rinterpretation of the facts, and the expression thereof in your piece,* ^1 d! Y/ E; E
explicitly or otherwise, but showing only evidence that favours your
; y7 Y1 k' d0 Z. F8 J8 yargument is hardly good science or journalism. Such an article in a journal
0 s' D5 Z. d. t4 h) Ksuch as Nature is not an appropriate example of how scientific research or
2 }/ b9 H) {' B/ f: y4 L( j2 J- treporting should be done. |
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