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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG. ]. A0 s; j' T) |5 r: H
如果是中国长大的,英语能到这种程度真是很不简单。
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& G. E3 k' |; R. k, Q" ?http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html, ^* k; Y! U' n: O
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania. n4 d$ _ t- n# j
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It is a shame to see Nature — which nearly all scientists, including myself
$ h9 ` g; T! u- {( o, regard as one of the most prestigious and influential physical-science
7 R; u# o8 ?+ S# W& P- F4 e' Lmagazines — publish a thinly veiled biased article like this. Granted, this
3 J9 l* O+ `1 o3 g& Cis not a peer-reviewed scientific article and did not go through the
6 {; R# s9 i9 f' @3 v2 w0 Hscrutiny of picking referees. But to serve as a channel for the general
2 |# z. G, R: j- c* K! Lpopulace to be in touch with and appreciate science, the authors and editors" [5 ?- F, X' u
should at least present the readers with facts within the proper context,
2 h& x; o" X0 Y: H7 D2 L: j0 o; ewhich they blatantly failed to do.; U9 p: x6 C3 I9 c) A, R$ R
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First, to identify Ye’s performance increase, Ewen Callaway compared her
; U# O% B e( k+ v6 \' L+ aOlympic 400-metre IM time with her performance at the World Championships in' D& T/ _3 t+ X. a5 u5 p' ^. E. X
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “( a1 g! T9 p9 q- _, K F% F0 _5 y
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
: z2 E- t1 f1 t! }8 U$ _, Fpersonal best was 4:33.79 at the Asian Games in 2010. This leads to an
: q# }; t S! j1 Ximprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the
- S" q; O4 m; i4 a) }6 n# q" `3 q _difference between the gold and silver medal, I see no reason for 5.38 s to2 h5 E2 W0 x* M9 D& y
be treated as 7 s.3 @5 \% u4 w! o6 @
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Second, as previously pointed out, Ye is only 16 years old and her body is
l8 I& c6 n( |, b! @& `5 Pstill developing. Bettering oneself by 5 seconds over two years may seem
, `4 a! ~+ F# G* w {+ Jimpossible for an adult swimmer, but it certainly happens among youngsters.8 g, p) Y2 m/ x7 `" @0 y& |0 P* p
An interview with Australian gold medallist Ian Thorpe revealed that his 400* y+ p" g) i3 z; |. ]
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
9 y; O& W. s6 a9 q' c: yFor regular people, including Callaway, it may be hard to imagine what an
2 g E! ^# d+ {0 j9 Belite swimmer can achieve as he or she matures and undergoes scientific and
3 a3 y2 O i- l; `' Z' I7 w% y p& Y5 Upersistent training. But jumping to the conclusion that it is “anomalous”1 g7 H1 @2 }3 {% y
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook8 v2 P) F* H9 T. j$ j' K5 V
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
. u0 y) G4 e: u4 ^/ Bthe last 50 metres, but Lochte had a huge lead in the first 300 metres, so* w! l! n$ L# p+ y
he chose not to push himself too hard and to conserve his energy for later9 N6 W) A8 G0 p' c
events (whether this conforms to the Olympic spirit and the ‘use one’s) q6 H$ n% N( x/ ] \
best efforts to win a match’ requirement that the Badminton World
# ~ X* V; {, P& rFederation recently invoked to disqualify four badminton pairs is another6 E/ l* N' j+ j6 k. s# m7 l
topic worth discussing, though probably not in Nature). Ye, on the other
$ g, n6 ], ?1 ^4 z" V/ xhand, was trailing behind after the first 300 metres and relied on freestyle
1 e, w/ N& c7 E s, in which she has an edge, to win the race. Failing to mention this
0 h3 h1 b( D! r9 N' u8 Fstrategic difference, as well as the fact that Lochte is 23.25 seconds0 s$ w% S4 E* H4 q/ N1 d& o- } |
faster (4:05.18) than Ye overall, creates the illusion that a woman swam- ]+ n; Z9 @! Y* p- Z2 Y
faster than the best man in the same sport, which sounds impossible. Putting1 ?# P& K& K$ K. W2 X
aside the gender argument, I believe this is still a leading question that# y( M ~+ b& D+ M
implies to the reader that there is something fishy going on.
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Fourth is another example of cherry-picking. In the same event, there are- e6 \5 c7 @! e7 C4 e5 ]# \0 e
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
# r/ o5 G0 U& p+ A1 P: Ns) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s' [: y4 N% U5 g2 i
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
) ^* P+ V, i$ v% bout, if we are just talking about the last 50 metres in a 400-metre IM,9 v; ^' t+ a7 L) E3 C% c/ j
Lochter is not the example I would have used if I were the author. What kind
( P6 b; t o3 T; q; h! m9 M) Vof scientific rigorousness is Callaway trying to demonstrate here? Is it6 D0 L( X# h7 D: U& ^6 n! D
logical that if Lochter is the champion, we should assume that he leads in3 m* W* a9 Z+ ]; P: b' d
every split? That would be a terrible way to teach the public how science
" t) M K1 o0 F9 ~1 jworks.
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and
) e' t- S6 T: ]( @implies that a drug test cannot rule out the possibility of doping. Is this' r' h( q. ]0 G# I5 c u$ y
kind of agnosticism what Nature really wants to teach its readers? By that3 _2 ]3 f; z W7 L! A
standard, I estimate that at least half of the peer-reviewed scientific- q5 o/ d9 w& t0 U. w& n9 {
papers in Nature should be retracted. How can one convince the editors and
! h. q4 @6 e/ w# q/ T& [reviewers that their proposed theory works for every possible case? One* Q5 ~, }1 Q6 p) `
cannot. One chooses to apply the theory to typical examples and to! |& w" w& ^+ w' x0 ~ Q
demonstrate that in (hopefully) all scenarios considered, the theory works- C6 t0 w$ ^4 L( `6 L! F
to a degree, and that that should warrant publication until a counterexample
$ i8 y0 O# `+ H1 W3 r. G# Jis found. I could imagine that Callaway has a sceptical mind, which is
& K3 ^# _$ A7 d6 D, e* jcrucial to scientific thinking, but that would be put to better use if he/ ?! k8 U/ ?* t1 ^& L0 U' p( L' A
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly1 q% s) M( O- p; W M9 a
advanced, non-detectable drug that the Chinese have come up with in the( C$ f/ V1 w- p+ X5 I% h; F
past 4 years (they obviously did not have it in Beijing, otherwise why not1 H, E/ t3 _% O& }
use it and woo the audience at home?), based on data and rational derivation
- N, Y' ~9 J# d+ O- o _. This article, however, can be interpreted as saying that all athletes are
" E; m& q9 i4 X8 M5 d9 S4 K5 ]: xdoping and the authorities are just not good enough to catch them. That may
9 Z Q3 l0 a$ h2 ebe true, logically, but definitely will not make the case if there is ever a4 C i- W7 i6 j1 B
hearing by the governing body for water sports, FINA, to determine if Ye5 I7 v: K p$ v9 ^: Q t& q
has doped. To ask whether it is possible to obtain a false negative in a
% j8 E: G ?) T7 u& r: y$ Y5 \drug test looks like a rigged question to me. Of course it is possible:
, o" m" R' ?, o: eother than the athlete taking a drug that the test is not designed to detect
$ Q4 C2 I9 E1 d8 u- e8 C/ _, anyone who has taken quantum 101 will tell you that everything is
! f2 |2 k! A5 v. b& Fprobabilistic in nature, and so there is a probability that the drug in an. Y y; r! C. W8 b$ D5 i* Y
athlete’s system could tunnel out right at the moment of the test. A slight s9 E: I) y- ?) d' p5 V% M4 T" V0 [
chance it may be, but should we disregard all test results because of it?
6 ?$ R& d7 E0 n; t) J* ^9 M( V, hLet’s be practical and reasonable, and accept that the World Anti-Doping
2 E( ]* E: }5 x+ o# \' zagency (WADA) is competent at its job. Ye’s urine sample will be stored for5 H+ F A" c" a+ Q5 E% N, _
eight years after the contest for future testing as technology advances.* E/ x. b% q5 @1 J! p1 `
Innocent until proven guilty, shouldn’t it be?6 E3 A% F2 L8 ]
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Sixth, and the last point I would like to make, is that the out-of-
! C" E7 X! K" W& p$ D. H* c$ u, acompetition drug test is already in effect, which Callaway failed to mention' B( `& [+ f7 s& C) @4 i
. As noted in the president of WADA’s press release, drug testing for2 {3 c- _# J* p3 [& i- G
Olympians began at least six months before the opening of the London
1 p9 Z) b3 O( K4 V+ xOlympics. Furthermore, 107 athletes have been banned from this Olympics for3 G9 M* W1 C& w; ~1 ~1 f1 J
doping. That may be the reason that “everyone will pass at the Olympic
( E. o0 Z. o, v! b" W* mgames. Hardly anyone fails in competition testing” — those who did dope
) x! n8 }" \" Z4 M. v/ yhave already been caught and sanctioned. Callaway is free to suggest that a
' ]5 ~9 g% Y" Q2 a8 ^player could have doped beforehand and fooled the test at the game, but this; i0 S: q* n) O `1 W% ?* V6 E
possibility is certainly ruled out for Ye.% L& C8 m" b5 \
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Over all, even though Callaway did not falsify any data, he did (
7 i% y) A9 s; `. p* rintentionally or not) cherry-pick data that, in my view, are far too
( Y. _% k9 G/ i; }0 X0 Z1 L, j- Psuggestive to be fair and unbiased. If you want to cover a story of a
, ?. R9 U; y' x8 bsuspected doping from a scientific point of view, be impartial and provide0 d; p& y/ U0 V8 V8 o: y/ F
all the facts for the reader to judge. You are entitled to your
) u! h- J, H7 P0 r3 I/ q8 zinterpretation of the facts, and the expression thereof in your piece,& `) V, ~) |) I2 {- x
explicitly or otherwise, but showing only evidence that favours your; V* z* X7 u' Z! z
argument is hardly good science or journalism. Such an article in a journal
! `# z1 [1 |- c0 W1 _& |$ A" Ysuch as Nature is not an appropriate example of how scientific research or& K! u. w- A ?5 U9 v
reporting should be done. |
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