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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
$ A" t1 a$ z3 X3 a如果是中国长大的,英语能到这种程度真是很不简单。- v# N" x7 I% D) k
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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! ~0 {7 Q: C4 VFROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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; G/ y3 x6 }8 H8 z7 A9 z' aIt is a shame to see Nature — which nearly all scientists, including myself
" c5 W7 i- i0 C- J- L; O7 E" P' @/ a, regard as one of the most prestigious and influential physical-science4 P+ x4 C) V* M) n. H6 @4 t
magazines — publish a thinly veiled biased article like this. Granted, this, t7 F. M9 ~' I$ D- ^/ M8 }/ @7 r( I9 `
is not a peer-reviewed scientific article and did not go through the* e: ~# J+ a1 u3 x" r% W8 ?9 @
scrutiny of picking referees. But to serve as a channel for the general
* a& ?5 Q5 d' N# G% {# _ Epopulace to be in touch with and appreciate science, the authors and editors# q; O( V! H# q& C% T; v
should at least present the readers with facts within the proper context,
/ ~; ~ m* B% c" R2 U5 Q9 ~which they blatantly failed to do./ j8 a) g5 L4 u/ | @
! v/ a) ?% [: r/ hFirst, to identify Ye’s performance increase, Ewen Callaway compared her
G# f& {* Q; E3 r5 Z4 `Olympic 400-metre IM time with her performance at the World Championships in5 \# G; {9 b1 I) c2 M! ~+ d3 t- l
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “- x5 O- X0 f8 C, e; f
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous! x* F T& T# H/ T( x! `9 o
personal best was 4:33.79 at the Asian Games in 2010. This leads to an! ?, u+ d5 z% _/ M$ V
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the* {5 N) e% n8 W# ~+ W! R6 v# O
difference between the gold and silver medal, I see no reason for 5.38 s to
% n; a" v# R9 v6 `0 }be treated as 7 s.' \, ~1 o, z/ I; o8 e" [2 d
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Second, as previously pointed out, Ye is only 16 years old and her body is
! n4 p! x$ E1 K/ Y0 L+ h9 ~still developing. Bettering oneself by 5 seconds over two years may seem
8 Q& E7 b$ B: t% A9 {/ g1 D2 Qimpossible for an adult swimmer, but it certainly happens among youngsters.- V9 Q+ o; Q! e$ L
An interview with Australian gold medallist Ian Thorpe revealed that his 400+ l6 M$ U+ m2 B$ i0 P
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
+ x$ K, s. F G/ ~- j4 FFor regular people, including Callaway, it may be hard to imagine what an* y* E, N/ L/ z) C, M, Z+ A
elite swimmer can achieve as he or she matures and undergoes scientific and
7 @5 B; \; t' L7 k- apersistent training. But jumping to the conclusion that it is “anomalous”
$ C, I3 c. r% j" b$ H% ybased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.$ x5 |6 `5 Z9 p
" m, W6 u, k# A! X4 VThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
& l+ u( C- L {! F, [example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in+ U2 \$ J1 s& \( m. v1 R! h7 c+ H* q
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so
6 i8 A3 N+ ~9 A) e3 d! E* yhe chose not to push himself too hard and to conserve his energy for later
7 I, L$ p# ^& n9 |/ X0 w t! Y- Pevents (whether this conforms to the Olympic spirit and the ‘use one’s
" w5 I w0 V4 B. f5 Vbest efforts to win a match’ requirement that the Badminton World
1 y/ @( c, [' ^Federation recently invoked to disqualify four badminton pairs is another
I+ w0 x4 m$ u! H) t3 B# p: Vtopic worth discussing, though probably not in Nature). Ye, on the other
4 M/ b" ^+ E# h# h. f \, a, B5 Ihand, was trailing behind after the first 300 metres and relied on freestyle
7 G, x1 b8 y2 u; O( ?) T, in which she has an edge, to win the race. Failing to mention this
& B$ L( }* t( Rstrategic difference, as well as the fact that Lochte is 23.25 seconds
( o1 X/ B+ T( E# ]8 gfaster (4:05.18) than Ye overall, creates the illusion that a woman swam
; n! M. L1 s+ Y; X4 ~faster than the best man in the same sport, which sounds impossible. Putting3 n9 k- r3 P8 n/ O" S% L
aside the gender argument, I believe this is still a leading question that
8 q1 G6 P5 X* O( X/ Pimplies to the reader that there is something fishy going on.
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Fourth is another example of cherry-picking. In the same event, there are8 u# i3 s* B' x) N
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93! g% D3 q; D$ t1 x0 V
s) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s- c! B2 {$ ~5 E; m
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns8 e$ [5 Y7 i7 ]- [( j
out, if we are just talking about the last 50 metres in a 400-metre IM,% G" C" I3 |' E& o$ ~' W
Lochter is not the example I would have used if I were the author. What kind5 L+ x( E! |! c. o4 m- |/ y
of scientific rigorousness is Callaway trying to demonstrate here? Is it
/ ]2 {# P& n# Vlogical that if Lochter is the champion, we should assume that he leads in
! n2 F( _( V; Aevery split? That would be a terrible way to teach the public how science4 O' a' z f# a# j4 S
works.; W: ^! E) G. F! D+ v/ Y$ r4 {
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and
3 f0 F0 q/ K. X$ Fimplies that a drug test cannot rule out the possibility of doping. Is this7 ~/ y% D6 y2 [. _# A8 `
kind of agnosticism what Nature really wants to teach its readers? By that M q2 v- r$ V
standard, I estimate that at least half of the peer-reviewed scientific
* e0 g- ^- q* W S% `' Q0 hpapers in Nature should be retracted. How can one convince the editors and
! E& G' B3 |9 X8 Sreviewers that their proposed theory works for every possible case? One
' s* r4 C. q k/ Z* M# \7 ~cannot. One chooses to apply the theory to typical examples and to" R9 D) t( z: ]2 Q! ~
demonstrate that in (hopefully) all scenarios considered, the theory works
# A5 Z& g- c3 o: f' v7 r# M, X( a: jto a degree, and that that should warrant publication until a counterexample, @9 P1 ~# _0 g( l( `7 q
is found. I could imagine that Callaway has a sceptical mind, which is
# k3 Y7 T1 {3 i9 i: X9 Ycrucial to scientific thinking, but that would be put to better use if he
( g4 A1 i7 k$ ]% d0 Swrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
/ U% G: n# k5 k- P9 P' R6 radvanced, non-detectable drug that the Chinese have come up with in the( T, A& W9 O7 Z$ N H# M: z
past 4 years (they obviously did not have it in Beijing, otherwise why not% k. A7 e4 L, @
use it and woo the audience at home?), based on data and rational derivation1 s, L; N, t: q& T' J! T
. This article, however, can be interpreted as saying that all athletes are$ U9 [) W/ I: x2 F* ~
doping and the authorities are just not good enough to catch them. That may0 f- |1 Y- f) i1 O
be true, logically, but definitely will not make the case if there is ever a
8 ^ F( i0 Z( Nhearing by the governing body for water sports, FINA, to determine if Ye
0 B5 M( ~, M1 G' l/ [has doped. To ask whether it is possible to obtain a false negative in a' I: h' f- t* c" N0 Y& o
drug test looks like a rigged question to me. Of course it is possible:
/ ^ L3 @" F4 Q5 Fother than the athlete taking a drug that the test is not designed to detect7 C3 a P5 }8 c; r6 ]& a$ z) s
, anyone who has taken quantum 101 will tell you that everything is8 v: S( P8 c, k- u' j1 _8 M- X
probabilistic in nature, and so there is a probability that the drug in an
2 C8 D' K* X' |* g! W$ [" W9 kathlete’s system could tunnel out right at the moment of the test. A slight
6 x1 }& M3 W8 h2 a. q3 T) }chance it may be, but should we disregard all test results because of it?
, S6 z' p7 }8 t9 [& tLet’s be practical and reasonable, and accept that the World Anti-Doping" T4 {* N- |* O. i4 Z
agency (WADA) is competent at its job. Ye’s urine sample will be stored for1 r5 |1 _) Y2 o, v
eight years after the contest for future testing as technology advances./ O% V, i' O3 Z3 N6 L L& i9 N2 y' q4 w
Innocent until proven guilty, shouldn’t it be?
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Sixth, and the last point I would like to make, is that the out-of-3 ]- k) r* I% J* [ ]* Q5 Q+ l
competition drug test is already in effect, which Callaway failed to mention2 f* I' s# i) J# Z
. As noted in the president of WADA’s press release, drug testing for
2 X6 d' Z; J9 p0 h; z0 mOlympians began at least six months before the opening of the London
( a+ z. a, X) L1 wOlympics. Furthermore, 107 athletes have been banned from this Olympics for
* E* X: l, R; C- @. D8 zdoping. That may be the reason that “everyone will pass at the Olympic9 W/ f( S1 h4 n6 l: T. [
games. Hardly anyone fails in competition testing” — those who did dope8 w- o- n4 T+ N' t$ ?
have already been caught and sanctioned. Callaway is free to suggest that a
3 \1 ^. F9 @. e; r) j) uplayer could have doped beforehand and fooled the test at the game, but this
4 _/ w& `$ Z& b" @possibility is certainly ruled out for Ye./ L9 o3 c ^- ]% Q5 {! i
0 ?+ F& H- O8 p/ D! P6 S DOver all, even though Callaway did not falsify any data, he did (
6 A' _: N v2 k1 xintentionally or not) cherry-pick data that, in my view, are far too
* ~5 [4 W* c* m7 G' osuggestive to be fair and unbiased. If you want to cover a story of a5 y1 z. y8 S) U
suspected doping from a scientific point of view, be impartial and provide
. ~9 P2 n1 f' T& P8 b, Aall the facts for the reader to judge. You are entitled to your
$ O7 ~5 {3 E L7 z/ ointerpretation of the facts, and the expression thereof in your piece,' q+ u5 K* W C& X! R8 d' c9 I5 I
explicitly or otherwise, but showing only evidence that favours your/ q, f8 K$ c( Z% A7 M; O
argument is hardly good science or journalism. Such an article in a journal
( c% Z G5 ^% dsuch as Nature is not an appropriate example of how scientific research or, F; @ x9 g$ d% i! h- h7 P1 R' a/ d( h# o
reporting should be done. |
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