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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG. f2 X6 s% ^- t( L* v8 s
如果是中国长大的,英语能到这种程度真是很不简单。7 ^$ Y8 {' o# T! ?9 O5 R
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania' W5 l! Z# K# {5 D2 a7 I
( W- ^, e% a# Q* J' E* ~6 T& jIt is a shame to see Nature — which nearly all scientists, including myself
0 G5 V5 g- K& |1 K+ x: p K* k, regard as one of the most prestigious and influential physical-science2 W5 G4 _/ X. k% V
magazines — publish a thinly veiled biased article like this. Granted, this
+ Z9 K2 z+ N4 f( O$ K$ _* yis not a peer-reviewed scientific article and did not go through the3 R& E/ ^# V8 V5 P& P& V
scrutiny of picking referees. But to serve as a channel for the general
2 c8 M4 q- C7 C1 L( {populace to be in touch with and appreciate science, the authors and editors2 Z S2 m, J3 {- D1 n0 o
should at least present the readers with facts within the proper context,# m, X2 @- h# u/ q4 x4 s1 U( e
which they blatantly failed to do.5 x6 `! h4 @( {0 y1 a( t! b
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First, to identify Ye’s performance increase, Ewen Callaway compared her
1 @% j4 v/ `3 a- IOlympic 400-metre IM time with her performance at the World Championships in; M# D- I" B1 g9 t3 O& W: F
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “1 C* y# Q! d& Y) H1 l- f$ S1 G
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
: t# d. }1 k' l) o/ ?2 Epersonal best was 4:33.79 at the Asian Games in 2010. This leads to an0 p3 u- j6 |7 W }4 O) q
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
+ h6 Y; O6 `6 y0 S6 ydifference between the gold and silver medal, I see no reason for 5.38 s to
* l' t0 S# N: e. b+ d0 m3 ?be treated as 7 s.
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Second, as previously pointed out, Ye is only 16 years old and her body is1 {4 y. f3 E0 R1 A! U+ }: _" N4 p) a6 V
still developing. Bettering oneself by 5 seconds over two years may seem0 C* r* }+ n) O/ {2 V
impossible for an adult swimmer, but it certainly happens among youngsters.6 O2 x* J) `- U
An interview with Australian gold medallist Ian Thorpe revealed that his 400$ {/ h" l9 H5 L c
-metre freestyle time improved by 5 seconds between the ages of 15 and 16." H. ] i- ]. l
For regular people, including Callaway, it may be hard to imagine what an
& h( A' z) x7 m3 y; y' Delite swimmer can achieve as he or she matures and undergoes scientific and" I. N* m4 O! n" Z" p2 d: L; I
persistent training. But jumping to the conclusion that it is “anomalous”
4 D) d# ]3 |% I6 ^based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook/ B6 w) r! l7 a$ Y: e2 ~% u- K! y
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
+ a6 [9 P! Z* p* M2 u( `3 wthe last 50 metres, but Lochte had a huge lead in the first 300 metres, so
& Y4 f: o5 ?* M e: e' z; g# ohe chose not to push himself too hard and to conserve his energy for later, S8 F* q3 _/ g
events (whether this conforms to the Olympic spirit and the ‘use one’s
# e) d; z; x- z8 s# y' r0 ?: \best efforts to win a match’ requirement that the Badminton World. G; Z: V: I) c! D0 F$ J0 W
Federation recently invoked to disqualify four badminton pairs is another, p2 m l" ?2 m( b; A t( ?
topic worth discussing, though probably not in Nature). Ye, on the other
) f/ M+ m, Y/ E7 T+ o) O }+ qhand, was trailing behind after the first 300 metres and relied on freestyle) \; @2 b# K# G4 c; ]) [
, in which she has an edge, to win the race. Failing to mention this8 `- {* s$ z) x! f9 j
strategic difference, as well as the fact that Lochte is 23.25 seconds
! |2 v: M1 q* h8 ^# q6 m# A$ t% t6 i+ cfaster (4:05.18) than Ye overall, creates the illusion that a woman swam9 t; x3 I" G4 \! k" B. a) J
faster than the best man in the same sport, which sounds impossible. Putting. I" Y) k$ O$ {$ S( x- [& ^
aside the gender argument, I believe this is still a leading question that
. S8 ^% w0 c( d0 [5 I$ V& v- qimplies to the reader that there is something fishy going on.$ e; C+ p0 r4 M
: t$ n9 l9 E7 F- A: dFourth is another example of cherry-picking. In the same event, there are
( j/ g, e/ \( B" o( Wfour male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
z4 F: Z- P, Z' i" ts) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s
" f E6 v, g) [4 ]), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
+ d9 i/ l" N3 B1 lout, if we are just talking about the last 50 metres in a 400-metre IM,0 ^3 i+ P$ a( @0 Q) p- J* I
Lochter is not the example I would have used if I were the author. What kind
8 c5 c" E4 x% Z- m0 \& ?2 wof scientific rigorousness is Callaway trying to demonstrate here? Is it8 J! @' r* R' K# V1 Q. R. I- m
logical that if Lochter is the champion, we should assume that he leads in
: B! X/ U; o R( O" H4 C) _) Aevery split? That would be a terrible way to teach the public how science! P( c, w3 z3 F0 l* y3 \$ R0 X. I
works.: s j' ^+ x8 T: Y' e! X1 g, R- j# E0 R
0 b: N( r- a2 g5 FFifth is the issue I oppose the most. Callaway quotes Ross Tucker and
. p4 |4 a3 v, e h9 Kimplies that a drug test cannot rule out the possibility of doping. Is this- a8 f& J: I. t' M% I$ K5 b! l& B& F
kind of agnosticism what Nature really wants to teach its readers? By that- P1 E& p6 b6 r
standard, I estimate that at least half of the peer-reviewed scientific/ J& p/ m4 k: R6 [4 r. n
papers in Nature should be retracted. How can one convince the editors and
4 r5 | L Y* {( lreviewers that their proposed theory works for every possible case? One
! u: c# G5 h v! s" Z, V1 d# @" C" Jcannot. One chooses to apply the theory to typical examples and to7 V6 _. v; S% _7 Q+ j0 r
demonstrate that in (hopefully) all scenarios considered, the theory works2 Z/ E W5 T: w& A
to a degree, and that that should warrant publication until a counterexample
1 z: Z& h' e( _" b+ k# Uis found. I could imagine that Callaway has a sceptical mind, which is8 R( H. P' q0 g! ]
crucial to scientific thinking, but that would be put to better use if he
/ x7 L: }2 J$ p; I9 B: R# pwrote a peer-reviewed paper that discussed the odds of Ye doping on a highly) }/ {5 v8 r1 j& u
advanced, non-detectable drug that the Chinese have come up with in the( K. s8 G; c. G9 l g; s
past 4 years (they obviously did not have it in Beijing, otherwise why not. n0 F1 ?* p# h8 P" }# L; c6 n
use it and woo the audience at home?), based on data and rational derivation( n5 r* N* R1 z$ g, ~$ a% j* i
. This article, however, can be interpreted as saying that all athletes are# t! S1 C/ a8 r" ^
doping and the authorities are just not good enough to catch them. That may \+ {$ ]# b9 K) f. J6 I
be true, logically, but definitely will not make the case if there is ever a9 A h% o7 Q3 {8 |2 i
hearing by the governing body for water sports, FINA, to determine if Ye
. `4 O* Y' b) B1 Q$ Ahas doped. To ask whether it is possible to obtain a false negative in a
: i' J. t7 U) t( O: Y' X$ s7 Pdrug test looks like a rigged question to me. Of course it is possible:
; I! [% d7 R, D1 j& q! e/ r2 w mother than the athlete taking a drug that the test is not designed to detect
/ t9 o6 d8 G$ L4 ?3 P/ o1 M, anyone who has taken quantum 101 will tell you that everything is2 g5 O3 N% N: \- U8 k, U
probabilistic in nature, and so there is a probability that the drug in an
% Q7 k: |" q# Iathlete’s system could tunnel out right at the moment of the test. A slight
2 G- G% j; e- y+ m9 X' J# ]/ bchance it may be, but should we disregard all test results because of it?
& ~ V/ H2 y( r- _6 ELet’s be practical and reasonable, and accept that the World Anti-Doping& [" K6 Y% M3 j. K- o" h8 n
agency (WADA) is competent at its job. Ye’s urine sample will be stored for0 P$ e$ l$ _! b, ]0 h2 Q0 Z
eight years after the contest for future testing as technology advances.7 E" H1 _0 q; z* @/ a- z3 \0 A, Y$ |
Innocent until proven guilty, shouldn’t it be?
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Sixth, and the last point I would like to make, is that the out-of-8 _2 o- ~% T/ P
competition drug test is already in effect, which Callaway failed to mention) \+ P7 r- R b4 M, x+ m
. As noted in the president of WADA’s press release, drug testing for2 @; m2 P! x: Q
Olympians began at least six months before the opening of the London
0 v8 w0 L/ X8 @6 p. a" xOlympics. Furthermore, 107 athletes have been banned from this Olympics for
' x) s7 j2 X3 D$ fdoping. That may be the reason that “everyone will pass at the Olympic* X* B: h6 T) J
games. Hardly anyone fails in competition testing” — those who did dope
3 b" \6 a6 c9 shave already been caught and sanctioned. Callaway is free to suggest that a
# N/ `* a. U# vplayer could have doped beforehand and fooled the test at the game, but this3 G# N1 {- n& {) O% P3 G0 l/ Q* K
possibility is certainly ruled out for Ye.% C2 ?5 |0 @. @' N: s
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Over all, even though Callaway did not falsify any data, he did (7 ?. {% U2 M! `
intentionally or not) cherry-pick data that, in my view, are far too
$ _9 {& \/ Z, e6 M1 k% U/ ^" N5 fsuggestive to be fair and unbiased. If you want to cover a story of a0 ^" C, \( c3 [) N2 p" \3 |, U
suspected doping from a scientific point of view, be impartial and provide
$ B: Q% E6 H+ W6 y/ k0 rall the facts for the reader to judge. You are entitled to your
6 v3 x" ]2 w/ B; i7 [interpretation of the facts, and the expression thereof in your piece,8 q8 j- Y/ p! |! p* N! Z& K
explicitly or otherwise, but showing only evidence that favours your
& U: g7 z* b) f( Gargument is hardly good science or journalism. Such an article in a journal
( d2 m. u9 k- X/ T: |" ]! e" ysuch as Nature is not an appropriate example of how scientific research or4 O6 C5 |6 b. P. U
reporting should be done. |
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