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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG; t3 ]6 d3 \! B8 {( Y, M
如果是中国长大的,英语能到这种程度真是很不简单。
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania7 u1 s8 ^, Y' t: V
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It is a shame to see Nature — which nearly all scientists, including myself
2 v1 R& Z/ F. n* u, x1 w4 R0 a$ s3 h, regard as one of the most prestigious and influential physical-science
& N3 D+ m! D, x0 q$ ^ w: amagazines — publish a thinly veiled biased article like this. Granted, this% F* E( m4 f* x! d( b0 i
is not a peer-reviewed scientific article and did not go through the
, Y. ^: b J! o. [2 i1 k' w! `6 tscrutiny of picking referees. But to serve as a channel for the general" G4 R. C0 a! ?: \: ^
populace to be in touch with and appreciate science, the authors and editors
9 ^0 Q( v2 I) hshould at least present the readers with facts within the proper context,
4 E# n8 U! {6 Q5 m- q3 _/ ^- D+ _# g7 Uwhich they blatantly failed to do.' [# W F% c8 K
6 x& Z7 @( D6 I/ X! nFirst, to identify Ye’s performance increase, Ewen Callaway compared her
5 D( {6 Q6 \3 X3 b* }3 A b; lOlympic 400-metre IM time with her performance at the World Championships in" {+ o6 M7 R& f9 u( P/ @9 n/ e
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “1 q: U6 }* N7 }0 ]
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
: ~8 w* ^ r3 @personal best was 4:33.79 at the Asian Games in 2010. This leads to an
: p- t$ L& Q6 A1 cimprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the6 R* N. d0 n3 a8 e/ H
difference between the gold and silver medal, I see no reason for 5.38 s to5 `. d; j+ r6 b! S7 B: [. f; V
be treated as 7 s.
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Second, as previously pointed out, Ye is only 16 years old and her body is6 I' U T, R& h \
still developing. Bettering oneself by 5 seconds over two years may seem
: g' o6 E" `: |: M9 _) fimpossible for an adult swimmer, but it certainly happens among youngsters., W5 y/ w4 @. e( G9 D2 g
An interview with Australian gold medallist Ian Thorpe revealed that his 400
2 G6 e \, s7 p-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
: [0 t5 |3 d8 n' JFor regular people, including Callaway, it may be hard to imagine what an' v2 y7 t, y: K4 P) e. o2 A2 k8 W
elite swimmer can achieve as he or she matures and undergoes scientific and
5 }; t; g& V5 B$ z5 K; apersistent training. But jumping to the conclusion that it is “anomalous” x. u* {6 n4 F
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.6 Q2 w/ Z9 W/ s
* M1 B$ t( o# b& t4 qThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
! s: ^# y8 N- K6 y9 Yexample of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
( \* i3 Z3 ~ Q) M7 z0 W {3 Hthe last 50 metres, but Lochte had a huge lead in the first 300 metres, so/ |! L' Z" ] y- w* b8 ^& b! I
he chose not to push himself too hard and to conserve his energy for later
* m( Y6 ^: K3 W5 b5 `0 V: }events (whether this conforms to the Olympic spirit and the ‘use one’s
) m9 [( K9 k# y# cbest efforts to win a match’ requirement that the Badminton World
+ v8 u! c8 p9 A, k2 ?Federation recently invoked to disqualify four badminton pairs is another9 g3 \) i1 s$ c( T2 u
topic worth discussing, though probably not in Nature). Ye, on the other
8 s; D) Z9 ^3 T% X! p7 z0 i) |0 j! Xhand, was trailing behind after the first 300 metres and relied on freestyle
4 u# c9 w5 o$ q5 m" j, in which she has an edge, to win the race. Failing to mention this2 v* u$ O1 p7 i* Y, L: Z( \
strategic difference, as well as the fact that Lochte is 23.25 seconds
* u( [# h k% ?faster (4:05.18) than Ye overall, creates the illusion that a woman swam% y! t; c$ ?! ^% ]2 G1 U
faster than the best man in the same sport, which sounds impossible. Putting- y, d% y1 J5 y3 h
aside the gender argument, I believe this is still a leading question that
: I! u# Z. D* S- k; y ?! Ximplies to the reader that there is something fishy going on.
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9 E4 I( }) a( {$ @, u5 XFourth is another example of cherry-picking. In the same event, there are
. F7 E& E$ T; Vfour male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
' d: S9 {9 X3 o0 S: Y* Gs) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s1 S) ?( L% k* _& T. w
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns; { E, k/ ]; T1 v! n8 G
out, if we are just talking about the last 50 metres in a 400-metre IM,5 X1 H' e |; z* d
Lochter is not the example I would have used if I were the author. What kind- L# _! y+ m6 }2 R5 D, i0 J; ~
of scientific rigorousness is Callaway trying to demonstrate here? Is it/ b3 m6 ?% h: T$ P! o8 W
logical that if Lochter is the champion, we should assume that he leads in
1 ~: T4 A7 `* k% J' S% u2 tevery split? That would be a terrible way to teach the public how science# {; o& C! s, g5 C
works.
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$ w2 m4 q7 s' L7 s9 |Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and% Z6 n* I- r: ]6 }! a
implies that a drug test cannot rule out the possibility of doping. Is this0 z; y9 ~/ x$ U' v6 J
kind of agnosticism what Nature really wants to teach its readers? By that7 Y3 `& h, U# N' ?% r
standard, I estimate that at least half of the peer-reviewed scientific" j" g3 G: y4 D# v" ^9 @2 R
papers in Nature should be retracted. How can one convince the editors and
. L2 q- H) z Areviewers that their proposed theory works for every possible case? One
) o n& C& a( ] j ncannot. One chooses to apply the theory to typical examples and to6 }+ O, J- r9 b; e! @6 I) n! y! R
demonstrate that in (hopefully) all scenarios considered, the theory works
, c: n1 p2 b! R8 x( G" u( s% R) f- r/ Rto a degree, and that that should warrant publication until a counterexample: f' G" Y6 Y1 j( n
is found. I could imagine that Callaway has a sceptical mind, which is
9 H/ z; C: \' N7 n/ X4 x1 }- Gcrucial to scientific thinking, but that would be put to better use if he
) y3 @$ M8 W5 l; j- y+ t1 b- c2 ywrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
4 b7 q' `) c# }# ?advanced, non-detectable drug that the Chinese have come up with in the: i+ R9 d- f. x" K# G+ C
past 4 years (they obviously did not have it in Beijing, otherwise why not$ w+ q6 _* p! q, I
use it and woo the audience at home?), based on data and rational derivation
" Y4 j; M7 P% o8 c8 W, @; t3 ]& m% q. This article, however, can be interpreted as saying that all athletes are) \0 q0 R8 c! }
doping and the authorities are just not good enough to catch them. That may- V, i9 u3 {9 f$ K0 n# _
be true, logically, but definitely will not make the case if there is ever a) s5 k+ a, \9 ^9 f( o
hearing by the governing body for water sports, FINA, to determine if Ye
) M7 s0 [; B6 T4 e# f4 b% H/ B( @5 Yhas doped. To ask whether it is possible to obtain a false negative in a' h+ t G* s5 T- a7 I5 N8 d
drug test looks like a rigged question to me. Of course it is possible:
* {- q; l; s& j' V1 N& ^# _other than the athlete taking a drug that the test is not designed to detect
8 |- V+ Y5 J, N; E, anyone who has taken quantum 101 will tell you that everything is9 ~$ A$ S5 m+ S0 [$ U0 @
probabilistic in nature, and so there is a probability that the drug in an
6 }% z% c2 R9 `2 bathlete’s system could tunnel out right at the moment of the test. A slight; |6 K3 {. t4 c( K" Q" o2 p5 h0 \
chance it may be, but should we disregard all test results because of it?% T; a/ {" J+ n+ U- M' a! y" A; h
Let’s be practical and reasonable, and accept that the World Anti-Doping
0 X9 a8 b a, @3 vagency (WADA) is competent at its job. Ye’s urine sample will be stored for# L4 u4 J- ?& k( l6 a3 ^
eight years after the contest for future testing as technology advances.
- |+ T0 A( f, M7 Y$ k. C" Q/ pInnocent until proven guilty, shouldn’t it be?" g/ \0 K# R6 ?. f1 r& i
% R1 P3 j# Q! V0 g- ]( }& O' sSixth, and the last point I would like to make, is that the out-of-
$ k) |* J" J1 C- p+ Icompetition drug test is already in effect, which Callaway failed to mention# k- V& C, V/ l: ~9 H: j- z% V
. As noted in the president of WADA’s press release, drug testing for% B l, \4 g% |: |6 w
Olympians began at least six months before the opening of the London
5 f9 m' _& R" N# UOlympics. Furthermore, 107 athletes have been banned from this Olympics for
5 ^$ C o+ h/ Jdoping. That may be the reason that “everyone will pass at the Olympic- @) L1 |) J2 j. G3 n6 z% D
games. Hardly anyone fails in competition testing” — those who did dope+ a7 \/ x2 v! h. Q* n* Q( f1 p
have already been caught and sanctioned. Callaway is free to suggest that a" _7 k! c! n$ X( }2 ^
player could have doped beforehand and fooled the test at the game, but this
$ { `- l2 p& n4 o4 L. K3 fpossibility is certainly ruled out for Ye.
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Over all, even though Callaway did not falsify any data, he did (
* v L3 p6 P8 M. n: W. f/ g8 O4 Rintentionally or not) cherry-pick data that, in my view, are far too
9 f! {+ G( y; H5 F* fsuggestive to be fair and unbiased. If you want to cover a story of a* m% |2 t: P' |8 U' {9 e
suspected doping from a scientific point of view, be impartial and provide2 C1 K7 o, |- q* M, \9 V
all the facts for the reader to judge. You are entitled to your
: O8 ~; F! w/ x% `3 y' minterpretation of the facts, and the expression thereof in your piece,3 }' w9 s6 K p& `$ H8 d; Y
explicitly or otherwise, but showing only evidence that favours your
0 V/ K2 b" B3 Largument is hardly good science or journalism. Such an article in a journal0 A9 d, Q9 B9 T9 ^ ~2 q
such as Nature is not an appropriate example of how scientific research or$ M4 u1 ~) F# v& s% I
reporting should be done. |
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