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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG0 z, f( P6 b+ e
如果是中国长大的,英语能到这种程度真是很不简单。/ z) `! t) P# ?: u. u) |
$ v" n, K" F) _& a' ihttp://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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4 D6 Q( x) S. @' S8 G0 ?: xFROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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& s7 q3 m; M2 x0 U! f8 [It is a shame to see Nature — which nearly all scientists, including myself
2 x6 L- N5 F; F \, regard as one of the most prestigious and influential physical-science2 [8 R6 r Y, `6 G
magazines — publish a thinly veiled biased article like this. Granted, this
1 |, V* [& ]6 \1 o3 Q# B o& |is not a peer-reviewed scientific article and did not go through the/ q6 O* s* Y. U
scrutiny of picking referees. But to serve as a channel for the general5 e: u' J' g3 K5 Z5 S; p" U$ ^
populace to be in touch with and appreciate science, the authors and editors% M+ a! g2 ~9 m0 ?3 r* N1 l
should at least present the readers with facts within the proper context,/ D. P% K0 z8 n9 n1 p9 D
which they blatantly failed to do.8 K7 m x4 z5 L0 ?. d6 w6 C6 |
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First, to identify Ye’s performance increase, Ewen Callaway compared her5 u% V6 z0 T* T& @) \; q8 J
Olympic 400-metre IM time with her performance at the World Championships in
2 @! j8 U/ J- j0 A2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
, F n2 G1 `4 Q% _anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous* W. G8 l5 H$ s. x F" [# Y
personal best was 4:33.79 at the Asian Games in 2010. This leads to an7 Y5 D8 B, F" j; s
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
1 c: f% R5 T: x; ^5 I' ?& Odifference between the gold and silver medal, I see no reason for 5.38 s to5 x8 H2 Z' `& n. |9 m4 S3 o
be treated as 7 s.
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! _7 @8 X" [4 r3 kSecond, as previously pointed out, Ye is only 16 years old and her body is
1 l _. |7 B# F2 T* ^) A) r5 ~still developing. Bettering oneself by 5 seconds over two years may seem
, q `/ {: Z- Timpossible for an adult swimmer, but it certainly happens among youngsters.
! b6 u- s& V& ~& n8 Z. q9 TAn interview with Australian gold medallist Ian Thorpe revealed that his 400; @6 c7 W. Z/ p c' I7 W6 @
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
4 @7 t% R% I: u! u* fFor regular people, including Callaway, it may be hard to imagine what an
: ~ T" N4 y* i2 C3 belite swimmer can achieve as he or she matures and undergoes scientific and
& u* W- d8 l- ~4 H% h; [& Apersistent training. But jumping to the conclusion that it is “anomalous”; \. V& T }6 i4 f/ @) j
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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4 q" s: f: _) k- T3 t' c' s5 W5 rThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
* s; p1 X* t k hexample of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in
0 r, T, `: @' M6 dthe last 50 metres, but Lochte had a huge lead in the first 300 metres, so8 z, k& r/ O8 w! }
he chose not to push himself too hard and to conserve his energy for later7 P3 y& S7 T$ N
events (whether this conforms to the Olympic spirit and the ‘use one’s1 R7 I! J# D0 ~ w0 l
best efforts to win a match’ requirement that the Badminton World
0 J6 w) n; H+ c4 k4 o+ k2 ^Federation recently invoked to disqualify four badminton pairs is another$ A* @" @9 e5 d+ E! _( E1 H& w
topic worth discussing, though probably not in Nature). Ye, on the other/ u) x, j( Y5 @) y# Y. M) Z7 H) M
hand, was trailing behind after the first 300 metres and relied on freestyle t5 Z# u, P# Z9 V, g
, in which she has an edge, to win the race. Failing to mention this/ z) s$ x; u9 z& c0 f+ M% q2 F
strategic difference, as well as the fact that Lochte is 23.25 seconds
' b8 f; s! M7 m1 l' rfaster (4:05.18) than Ye overall, creates the illusion that a woman swam
5 w' ~% {' I0 u6 T- dfaster than the best man in the same sport, which sounds impossible. Putting' `7 U" z1 _1 q
aside the gender argument, I believe this is still a leading question that$ \; h9 M* X2 @7 P, ^3 Y
implies to the reader that there is something fishy going on.2 g" X' F8 O/ c w, v4 B9 |
O7 ]7 O( m- j7 v# bFourth is another example of cherry-picking. In the same event, there are1 C# X6 p8 I$ _; f1 W1 J) P1 A, \% ?
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.935 p/ N* e& i/ [. v0 u
s) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s
9 _" b+ a$ C5 K0 K5 W), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
( O" ~: e+ @2 c* r+ Pout, if we are just talking about the last 50 metres in a 400-metre IM,* J) l L- g7 @
Lochter is not the example I would have used if I were the author. What kind1 o! q2 P7 M. ~0 s1 a
of scientific rigorousness is Callaway trying to demonstrate here? Is it( {0 @* {0 w5 w/ f' m: b3 W
logical that if Lochter is the champion, we should assume that he leads in
' q- s% M9 B) r4 ]: N: Revery split? That would be a terrible way to teach the public how science, {' o/ F* X) c1 l. J9 i: L9 J
works.
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: j( E- v' m1 Q7 l: wFifth is the issue I oppose the most. Callaway quotes Ross Tucker and/ F2 ^4 k. _- t3 @6 `4 k( Q
implies that a drug test cannot rule out the possibility of doping. Is this
7 A& S- h! ?* v, M# v9 g K. Qkind of agnosticism what Nature really wants to teach its readers? By that9 ]6 m% {% Z! W7 C3 }3 E
standard, I estimate that at least half of the peer-reviewed scientific
5 Q0 w+ \# s7 H& G* V/ jpapers in Nature should be retracted. How can one convince the editors and
) q5 q8 T, }! F! Y) ~reviewers that their proposed theory works for every possible case? One, [) Z8 p& N& X. R# k$ n- P8 w
cannot. One chooses to apply the theory to typical examples and to+ U9 K- M9 o/ A4 j+ {1 h* H6 Z) |
demonstrate that in (hopefully) all scenarios considered, the theory works
. b2 j2 U* d: xto a degree, and that that should warrant publication until a counterexample$ w$ ?& B5 q9 ~: _" U
is found. I could imagine that Callaway has a sceptical mind, which is% E1 e; ~+ W o6 j# ^
crucial to scientific thinking, but that would be put to better use if he
: ]2 D0 o" B0 i- F1 X& Z Owrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
) R, Q0 J: V6 R6 vadvanced, non-detectable drug that the Chinese have come up with in the
$ ]$ r2 Z3 ]. e4 c' z2 J6 Lpast 4 years (they obviously did not have it in Beijing, otherwise why not0 z+ G( I3 O# Q" }6 ~2 Z0 W1 t. i
use it and woo the audience at home?), based on data and rational derivation
4 f. O! q" ~% M. v. This article, however, can be interpreted as saying that all athletes are, U2 M5 t0 N0 N7 s
doping and the authorities are just not good enough to catch them. That may
e P9 p; z4 I- {8 Bbe true, logically, but definitely will not make the case if there is ever a: y: ?- _) Z% W% X9 w0 j3 @- N
hearing by the governing body for water sports, FINA, to determine if Ye; U) A8 z& B/ F! U
has doped. To ask whether it is possible to obtain a false negative in a
) l1 E9 V, D8 m8 }7 Ndrug test looks like a rigged question to me. Of course it is possible:% W: z( A5 i+ g8 Q
other than the athlete taking a drug that the test is not designed to detect
, p0 F( a1 o. I' Q4 [, anyone who has taken quantum 101 will tell you that everything is
. Y) ^0 b& X: Fprobabilistic in nature, and so there is a probability that the drug in an
* e: ]2 \, S5 h6 i" }athlete’s system could tunnel out right at the moment of the test. A slight4 f& B; Y) N1 b* [
chance it may be, but should we disregard all test results because of it?% l ]3 J1 {1 y0 b+ |9 [" {' Z
Let’s be practical and reasonable, and accept that the World Anti-Doping: R9 u/ B, {5 ^# }8 _* b% X8 T' ~: ^
agency (WADA) is competent at its job. Ye’s urine sample will be stored for
+ k0 O& q) S4 c3 Z& [eight years after the contest for future testing as technology advances.
. j6 d. x/ D9 v/ F9 d. ~Innocent until proven guilty, shouldn’t it be?) I+ \3 X% c# t1 Z8 p* W8 h- Z: Z: c$ r
, Q% B' f/ s! I1 V0 ?( RSixth, and the last point I would like to make, is that the out-of-. y9 c+ w) `: K: f
competition drug test is already in effect, which Callaway failed to mention
0 d/ Q% u9 E8 ^: E4 S2 ~2 k. As noted in the president of WADA’s press release, drug testing for+ G" g: S$ ?. R7 t
Olympians began at least six months before the opening of the London
) n9 S2 q. t. F" G6 [! p7 P) ^Olympics. Furthermore, 107 athletes have been banned from this Olympics for2 j4 Y/ \0 u. U
doping. That may be the reason that “everyone will pass at the Olympic
( k6 `4 ^1 |6 N) u. L; M. w$ Vgames. Hardly anyone fails in competition testing” — those who did dope9 z& G) X& Z* X+ c, N6 d' K
have already been caught and sanctioned. Callaway is free to suggest that a
* V1 d/ d3 ]! @( dplayer could have doped beforehand and fooled the test at the game, but this
# K. e, R: g% v1 j1 Ypossibility is certainly ruled out for Ye.
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4 a, P# e, m$ b( \8 KOver all, even though Callaway did not falsify any data, he did (
" S& v7 l# M* _* _intentionally or not) cherry-pick data that, in my view, are far too
( b/ D# T* t8 z7 t# N( Usuggestive to be fair and unbiased. If you want to cover a story of a
1 {% l+ I9 t6 t8 Y* esuspected doping from a scientific point of view, be impartial and provide
6 {. Z% e% G( n- N! ?all the facts for the reader to judge. You are entitled to your
, S! W- s) T" Z5 A9 b& Winterpretation of the facts, and the expression thereof in your piece,, U" J) C/ ]! R! ]
explicitly or otherwise, but showing only evidence that favours your
8 i5 Z8 v% E( w% |argument is hardly good science or journalism. Such an article in a journal8 w/ b2 C; ~; p2 r9 f; F- L6 z9 N
such as Nature is not an appropriate example of how scientific research or. t/ p2 H* S" P, \; {
reporting should be done. |
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