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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG( |" v+ `6 i# E8 W2 s3 a) u
如果是中国长大的,英语能到这种程度真是很不简单。! x4 H/ S# b3 T. X1 v1 G
c5 X; Z- T {+ G9 y: rhttp://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html3 i& Y$ E7 F* d
8 L- {. b; k5 t1 _4 p3 h) KFROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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* n+ C7 D a% C/ G0 D5 c# S7 ~. u8 FIt is a shame to see Nature — which nearly all scientists, including myself
) s+ q0 n( b$ G0 t& q2 Y, regard as one of the most prestigious and influential physical-science9 m8 k# o$ Y0 q
magazines — publish a thinly veiled biased article like this. Granted, this2 d4 x- ?2 [& K$ ^* f: i! K. L
is not a peer-reviewed scientific article and did not go through the
3 ^' F- E* I+ n% e3 `# g, A1 Rscrutiny of picking referees. But to serve as a channel for the general2 E) E: {0 s6 ?# u
populace to be in touch with and appreciate science, the authors and editors5 q( a$ O: ?4 t+ b! y6 t
should at least present the readers with facts within the proper context,! W, U7 x! I" a) p) `5 ~
which they blatantly failed to do., N0 M, I R9 }0 K
" y2 d: X0 u1 S2 kFirst, to identify Ye’s performance increase, Ewen Callaway compared her* e0 ~* S9 j2 j8 y
Olympic 400-metre IM time with her performance at the World Championships in
$ }% y4 J8 Y* ?7 ]7 ~$ N) z3 E2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “' ^7 [9 g- P* R7 @4 M8 u
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
+ c% T$ D0 ~6 F9 y& X' l# _personal best was 4:33.79 at the Asian Games in 2010. This leads to an2 h, N: S( e7 z, b( |
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
5 Z( S# }) K. T, `3 n5 W" ?difference between the gold and silver medal, I see no reason for 5.38 s to
3 Y) b# s& L1 J9 Pbe treated as 7 s.& t$ o+ C; V# h7 s
- B3 z5 Y' T; ~1 rSecond, as previously pointed out, Ye is only 16 years old and her body is! U. g3 y& T4 L O
still developing. Bettering oneself by 5 seconds over two years may seem* B! O8 \ f5 ]+ s- k
impossible for an adult swimmer, but it certainly happens among youngsters.
" I% k5 z" y. h$ E1 q* q- sAn interview with Australian gold medallist Ian Thorpe revealed that his 400 Z+ L( |4 X" b3 _) B: g3 G9 n; D; z
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.
! q4 w6 L& p& k3 Z& y% [For regular people, including Callaway, it may be hard to imagine what an" q' d* I; U; y9 i0 K' x: c. y
elite swimmer can achieve as he or she matures and undergoes scientific and4 J6 p5 P3 F) u# i
persistent training. But jumping to the conclusion that it is “anomalous”
2 B/ Y5 G; w- {) B7 P. nbased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.2 b8 ~* v5 X6 y0 `
; M D5 F$ G+ F. P5 D: g$ z/ jThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook4 V* R- A' O2 V. n; p+ ^
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in/ W0 n% V' g. Z$ q, I9 p! |2 i
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so/ L& [2 s2 t! Z( S0 X# ~8 `
he chose not to push himself too hard and to conserve his energy for later
H/ m2 D v/ devents (whether this conforms to the Olympic spirit and the ‘use one’s
# r% \1 }: m- Ibest efforts to win a match’ requirement that the Badminton World
% y. B0 j* e: R& {3 ]5 h$ vFederation recently invoked to disqualify four badminton pairs is another
" F0 Q& l* o) p6 r \topic worth discussing, though probably not in Nature). Ye, on the other; S2 g6 `& s" o9 ~; ?
hand, was trailing behind after the first 300 metres and relied on freestyle' |: [& a; n) m, h
, in which she has an edge, to win the race. Failing to mention this, s8 b/ p$ X- V6 A( Q' T
strategic difference, as well as the fact that Lochte is 23.25 seconds
. w& H8 [ \" A3 Mfaster (4:05.18) than Ye overall, creates the illusion that a woman swam
1 h& _% W- H) I+ W2 O$ c5 t+ Ofaster than the best man in the same sport, which sounds impossible. Putting6 P/ Y5 j& W( B. g
aside the gender argument, I believe this is still a leading question that
1 y8 O$ @* G" t# d: jimplies to the reader that there is something fishy going on.2 r+ g( h j+ C& D4 i9 q: I* w
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Fourth is another example of cherry-picking. In the same event, there are
! P- J- {% C3 L2 gfour male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
& X9 X6 k) R* ^2 d5 p# v; O5 a4 is) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s8 r- S- L1 u' S! e* ^
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns/ \, I4 r5 i, K% e* k% b
out, if we are just talking about the last 50 metres in a 400-metre IM,
5 r+ ?5 x( C* q% c5 ?! w: OLochter is not the example I would have used if I were the author. What kind
( _8 Q: a& W" n9 `' |9 H; W* hof scientific rigorousness is Callaway trying to demonstrate here? Is it! ~9 L5 X6 [; {+ |3 T0 W9 Z
logical that if Lochter is the champion, we should assume that he leads in$ @1 p) [1 h9 \( D
every split? That would be a terrible way to teach the public how science
9 E7 I3 y8 A9 @% H0 V5 L6 Jworks.
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' X, k x; I4 E2 VFifth is the issue I oppose the most. Callaway quotes Ross Tucker and
2 w' z3 |! q1 M2 M5 A- Dimplies that a drug test cannot rule out the possibility of doping. Is this
n- z4 ^/ Z8 O3 j5 d w/ Xkind of agnosticism what Nature really wants to teach its readers? By that
7 M) w( r$ q" s7 Hstandard, I estimate that at least half of the peer-reviewed scientific
/ o2 Y$ Z! j2 g- S; spapers in Nature should be retracted. How can one convince the editors and$ _9 h+ X; \3 f) Z) }+ c# X( [
reviewers that their proposed theory works for every possible case? One) q: U+ C& d9 {+ ~( ]5 e/ {
cannot. One chooses to apply the theory to typical examples and to7 j+ {; A2 @0 N3 B% A
demonstrate that in (hopefully) all scenarios considered, the theory works
" ^8 r+ y9 q+ I2 H; {0 Yto a degree, and that that should warrant publication until a counterexample! z& }/ ~$ ?6 U3 ?- w/ M* V
is found. I could imagine that Callaway has a sceptical mind, which is/ T: b& [' f: y" J3 S0 ?. A8 G
crucial to scientific thinking, but that would be put to better use if he$ i' h. J. _% A# c- I) ^
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly) L. }# B2 X! ?
advanced, non-detectable drug that the Chinese have come up with in the% o* _! r' r! r( i/ i1 b$ C
past 4 years (they obviously did not have it in Beijing, otherwise why not
, x' Z/ L4 \( l" n1 i) b+ tuse it and woo the audience at home?), based on data and rational derivation9 [8 l' X, b5 q7 |% M- h8 C
. This article, however, can be interpreted as saying that all athletes are* `1 q' _1 y+ b. G$ l* G
doping and the authorities are just not good enough to catch them. That may& e" @9 ?1 ~0 X2 Y0 k
be true, logically, but definitely will not make the case if there is ever a
- V! ~+ o! {# z+ o1 X* V Bhearing by the governing body for water sports, FINA, to determine if Ye6 ?9 ~( m+ y1 X
has doped. To ask whether it is possible to obtain a false negative in a
* @5 F/ \" |* Z1 a8 E) W4 _9 idrug test looks like a rigged question to me. Of course it is possible:3 `% d( j, |: d9 q! N
other than the athlete taking a drug that the test is not designed to detect6 v8 v& `& J6 `9 @8 M! Q
, anyone who has taken quantum 101 will tell you that everything is
% H6 q) j3 e( ^: S( n8 b1 sprobabilistic in nature, and so there is a probability that the drug in an
9 u1 L( C8 F6 W! X3 l7 V. I2 B. ~5 ]athlete’s system could tunnel out right at the moment of the test. A slight
1 j( A# Y: R" w" Achance it may be, but should we disregard all test results because of it?
) k# A. n# L# P' Y9 }2 k" ULet’s be practical and reasonable, and accept that the World Anti-Doping6 W& y- s1 C/ I$ [" x% n9 v
agency (WADA) is competent at its job. Ye’s urine sample will be stored for
' z( _6 T% ?3 geight years after the contest for future testing as technology advances.
5 h* R! Y1 {; U9 y% RInnocent until proven guilty, shouldn’t it be?+ {0 i& K L/ b2 l9 B3 d
9 S+ P u1 v3 P5 ^Sixth, and the last point I would like to make, is that the out-of-, g# I ~5 V5 L w
competition drug test is already in effect, which Callaway failed to mention4 R: h; {) F: N. U2 R; q0 w
. As noted in the president of WADA’s press release, drug testing for2 A5 a6 D% J* Z! K1 O3 ]3 A
Olympians began at least six months before the opening of the London
0 H. A! R/ \/ POlympics. Furthermore, 107 athletes have been banned from this Olympics for- N7 a( c: \1 Y: k, K* l
doping. That may be the reason that “everyone will pass at the Olympic: B, y6 k3 E6 G) u2 s9 M/ N4 V
games. Hardly anyone fails in competition testing” — those who did dope
* B/ [) ?8 c3 @3 I4 Q, }have already been caught and sanctioned. Callaway is free to suggest that a
3 K3 H$ e) q7 t1 y4 C; H/ P7 i0 Splayer could have doped beforehand and fooled the test at the game, but this
. [) @, p7 H! t4 s. epossibility is certainly ruled out for Ye.
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Over all, even though Callaway did not falsify any data, he did (
+ i9 V# t. ^# d$ E. pintentionally or not) cherry-pick data that, in my view, are far too
$ b: \1 H3 s+ y9 u# s3 Gsuggestive to be fair and unbiased. If you want to cover a story of a
9 k1 @5 j2 D9 zsuspected doping from a scientific point of view, be impartial and provide
) l4 U0 [: d+ oall the facts for the reader to judge. You are entitled to your
0 C- M' e0 F$ {. yinterpretation of the facts, and the expression thereof in your piece,; S& ?% `& X" f4 f8 _+ L! r6 |" ]0 S8 ~
explicitly or otherwise, but showing only evidence that favours your! ^8 t2 J3 H0 b0 m2 N8 T- Z, M
argument is hardly good science or journalism. Such an article in a journal
, i W" i9 m! V. l# |/ rsuch as Nature is not an appropriate example of how scientific research or; a+ @8 |" M: y {; Q( Z. y4 y6 y' Y, |
reporting should be done. |
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