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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG3 V# W, H: D! V: y
如果是中国长大的,英语能到这种程度真是很不简单。% x. R6 T! ]! X: F. C8 z: i
( I6 ~9 o2 r' uhttp://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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It is a shame to see Nature — which nearly all scientists, including myself
3 k- q! |4 w# @" @% K, A5 j, regard as one of the most prestigious and influential physical-science
7 u t6 y( z) q. S8 @magazines — publish a thinly veiled biased article like this. Granted, this
! i! K' M: u# Y0 t9 y+ O. I9 Cis not a peer-reviewed scientific article and did not go through the
z/ Y ?4 k4 ?6 l/ Y* dscrutiny of picking referees. But to serve as a channel for the general* F9 L' u2 S, u' P
populace to be in touch with and appreciate science, the authors and editors
5 S z: F0 l* ?: D: Wshould at least present the readers with facts within the proper context,
, R0 v7 a) ^; ?" N1 E! k2 g$ Awhich they blatantly failed to do.
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* j* B* k& S. }0 R- e5 ]' UFirst, to identify Ye’s performance increase, Ewen Callaway compared her
1 r, R" ~ ^4 V; F7 \- K0 `8 COlympic 400-metre IM time with her performance at the World Championships in
! B( L) ?$ `* y( {* [2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
) q# w. m, A! j% _8 l' l% qanomalous” improvement of around 7 seconds (6.72 s). In fact, her previous$ s N Y; I( ]5 c
personal best was 4:33.79 at the Asian Games in 2010. This leads to an* u6 Q2 @9 d, o5 ^# J) F
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
6 u9 y9 O! l' f1 u% V2 Jdifference between the gold and silver medal, I see no reason for 5.38 s to5 i$ ]. s) D l
be treated as 7 s.3 O% x* H9 m7 K4 _* P- q6 i, D! n
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Second, as previously pointed out, Ye is only 16 years old and her body is
- D! k* T. c/ h, q8 [& r. n: xstill developing. Bettering oneself by 5 seconds over two years may seem/ ?: R! M1 v3 ^: s4 U+ q
impossible for an adult swimmer, but it certainly happens among youngsters.
1 \- [1 F8 v9 L4 NAn interview with Australian gold medallist Ian Thorpe revealed that his 4004 _- }( G$ a: S1 e8 d
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.: k/ X. _; h, x: }& q5 r5 o
For regular people, including Callaway, it may be hard to imagine what an7 B1 n0 X+ T! _: J- G
elite swimmer can achieve as he or she matures and undergoes scientific and3 b1 M! Z' H( v# ` b' ? I" n
persistent training. But jumping to the conclusion that it is “anomalous”
, {8 z9 J8 P3 {8 b% L. c* Lbased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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Third, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook: @. S+ h! Z2 c" m
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in2 E8 O+ H Z# a0 |
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so( S& x6 h- Z h+ P2 Y
he chose not to push himself too hard and to conserve his energy for later
5 \' }8 Q4 p2 ]( V9 h; A% Z' Bevents (whether this conforms to the Olympic spirit and the ‘use one’s
3 K" o- L$ b5 z& c$ e; cbest efforts to win a match’ requirement that the Badminton World7 j% j' i* x) A/ V1 O
Federation recently invoked to disqualify four badminton pairs is another: c4 H \2 T- n
topic worth discussing, though probably not in Nature). Ye, on the other: \/ ~+ ]8 b5 Z: h' |( F4 i( `
hand, was trailing behind after the first 300 metres and relied on freestyle! f/ g' _2 J( T3 a
, in which she has an edge, to win the race. Failing to mention this
, `) P) M: |' B: Lstrategic difference, as well as the fact that Lochte is 23.25 seconds
% G1 F% _3 i% d# w) ~" L4 X1 w9 |faster (4:05.18) than Ye overall, creates the illusion that a woman swam% }8 |" B& F" Y# T. L, ~7 M& ~: R
faster than the best man in the same sport, which sounds impossible. Putting
4 [5 b, q% N# R, Laside the gender argument, I believe this is still a leading question that9 u4 b7 \/ d- _5 J, a, _
implies to the reader that there is something fishy going on.! c6 B; L$ \& A5 _( e$ h
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Fourth is another example of cherry-picking. In the same event, there are
% O: |6 B' t f( {) Nfour male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93# x( M3 |1 h( N5 \+ T
s) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s' ]' b. w" g: u2 r* z9 P2 h
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns4 I: ?7 d# o2 T5 e; H; ^% x: Z
out, if we are just talking about the last 50 metres in a 400-metre IM,
- p7 b+ ]: V- t( u2 @9 zLochter is not the example I would have used if I were the author. What kind6 V- J) o7 [" U7 P: z
of scientific rigorousness is Callaway trying to demonstrate here? Is it
" P& S' n' D! Q0 ?logical that if Lochter is the champion, we should assume that he leads in
, Z' n( K0 W/ t. _ ~every split? That would be a terrible way to teach the public how science. [$ G- W) L, q3 _, i& I. M
works.9 y% R3 e. E n
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and
# d! v$ T6 G! v; E# Simplies that a drug test cannot rule out the possibility of doping. Is this
, ~: Y9 P$ W) X) dkind of agnosticism what Nature really wants to teach its readers? By that, q6 B% J% s0 v# c
standard, I estimate that at least half of the peer-reviewed scientific7 q, s( k2 u( d+ ^5 ^! S* a
papers in Nature should be retracted. How can one convince the editors and
) T4 p2 O y' U4 Y2 d: J$ N& x/ hreviewers that their proposed theory works for every possible case? One
, s# _7 ^0 |1 k! t( n& ecannot. One chooses to apply the theory to typical examples and to' q) N; H+ s9 E! Z" o1 P4 d% T8 M
demonstrate that in (hopefully) all scenarios considered, the theory works
: ]9 O1 t4 D$ O. o) c* `to a degree, and that that should warrant publication until a counterexample' @; T% [( `3 J: ?1 `' T! Y. o. F& U
is found. I could imagine that Callaway has a sceptical mind, which is7 X0 [$ A" {9 A$ Z! f
crucial to scientific thinking, but that would be put to better use if he
9 K# f) p( H1 z# Y$ kwrote a peer-reviewed paper that discussed the odds of Ye doping on a highly" O6 k2 U$ k, [1 f% i% Z0 O
advanced, non-detectable drug that the Chinese have come up with in the
3 V1 r8 L2 `6 [' qpast 4 years (they obviously did not have it in Beijing, otherwise why not% G0 ]6 C! @3 v
use it and woo the audience at home?), based on data and rational derivation* k8 g* t$ ?8 L! @$ s! t
. This article, however, can be interpreted as saying that all athletes are
, C* {# E- d- ~+ t' C( c( q% Hdoping and the authorities are just not good enough to catch them. That may
: q3 A2 Q+ t9 b4 V- x3 [be true, logically, but definitely will not make the case if there is ever a
0 k ]+ \8 i2 |& ^hearing by the governing body for water sports, FINA, to determine if Ye
% S" P- c% C3 H! fhas doped. To ask whether it is possible to obtain a false negative in a
3 K( h! w5 |8 I3 t; f2 b5 kdrug test looks like a rigged question to me. Of course it is possible:2 J/ |6 f& q% M7 F8 d
other than the athlete taking a drug that the test is not designed to detect
- C! q) N7 H* O$ U: ?, anyone who has taken quantum 101 will tell you that everything is( X: N$ P H$ @6 A- [ D- N [
probabilistic in nature, and so there is a probability that the drug in an0 t8 F" D T; u+ j; |$ c' J. R
athlete’s system could tunnel out right at the moment of the test. A slight
% V- g$ l* p& H d2 p7 ?chance it may be, but should we disregard all test results because of it? F+ G# G4 {5 p2 c& O: m& \/ H
Let’s be practical and reasonable, and accept that the World Anti-Doping
! s$ g7 O3 I1 i& Oagency (WADA) is competent at its job. Ye’s urine sample will be stored for; v8 z( h6 q0 ?4 \( b+ R/ W
eight years after the contest for future testing as technology advances.. _- S. U3 k- K9 g
Innocent until proven guilty, shouldn’t it be?8 n v. a+ W9 s+ h, \6 U* Z0 m
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Sixth, and the last point I would like to make, is that the out-of-
" {7 d1 w$ S M! K) D8 n) _" gcompetition drug test is already in effect, which Callaway failed to mention
! {+ S7 t) _7 T. As noted in the president of WADA’s press release, drug testing for
3 Z% | t$ ?2 T6 c: }9 w$ NOlympians began at least six months before the opening of the London
) c+ n8 j+ i% b/ P$ b- a2 W5 M8 ROlympics. Furthermore, 107 athletes have been banned from this Olympics for
2 O) K, F, Z. o0 f; o7 L! Odoping. That may be the reason that “everyone will pass at the Olympic' q5 `/ v' |4 N
games. Hardly anyone fails in competition testing” — those who did dope# ?# [$ j3 g" R+ p) G
have already been caught and sanctioned. Callaway is free to suggest that a: q! ~- m7 U5 P$ Z" j* T
player could have doped beforehand and fooled the test at the game, but this
3 e; n* ^ n) k7 W. W/ |8 Opossibility is certainly ruled out for Ye.
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Over all, even though Callaway did not falsify any data, he did (- Z9 Y6 }: b" O: k
intentionally or not) cherry-pick data that, in my view, are far too6 `7 z& X0 |6 U: w% @* j' `
suggestive to be fair and unbiased. If you want to cover a story of a
. ~ L" D( w6 O- Nsuspected doping from a scientific point of view, be impartial and provide
6 r/ i V. a. Y0 k3 X$ ~0 ball the facts for the reader to judge. You are entitled to your! V2 h8 o5 s \( M8 t, G* c
interpretation of the facts, and the expression thereof in your piece,, _- b" X1 d4 {- q; C+ ^6 R
explicitly or otherwise, but showing only evidence that favours your
% o, {8 P/ i: U' M( B# M( K+ Bargument is hardly good science or journalism. Such an article in a journal: a, ?% Z+ f- q9 k/ Q* _7 W
such as Nature is not an appropriate example of how scientific research or
/ p8 I/ ~8 r& E- k4 Hreporting should be done. |
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