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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG1 Q8 ]# O! c+ ~$ y* A+ f% J
如果是中国长大的,英语能到这种程度真是很不简单。4 N' ]+ M7 O8 }& A) q' J
; P* [/ W- T& s" X7 rhttp://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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( U0 } `) j% c+ C/ ~It is a shame to see Nature — which nearly all scientists, including myself
& b n; v, l4 [- f6 K/ C! r, regard as one of the most prestigious and influential physical-science3 V0 X4 @& G5 r8 ]4 l W
magazines — publish a thinly veiled biased article like this. Granted, this2 b$ b+ V, `6 {1 k- A
is not a peer-reviewed scientific article and did not go through the) ], [: V7 U0 s8 K
scrutiny of picking referees. But to serve as a channel for the general- _* }5 ~, D0 Y4 o1 _. U6 _4 p
populace to be in touch with and appreciate science, the authors and editors
7 T: [+ o3 @% b7 X/ D Sshould at least present the readers with facts within the proper context,
. j# {* z3 V$ Y9 ~. {- ^/ E$ ~which they blatantly failed to do.
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First, to identify Ye’s performance increase, Ewen Callaway compared her
6 _, y- u! n) h3 l( T& DOlympic 400-metre IM time with her performance at the World Championships in& T+ Z9 O. x( y- ~4 _3 f
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “, U7 `; y* R+ _5 t' I8 w) W
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
4 H0 s+ h( J/ r5 f- a/ \9 Y8 I+ Dpersonal best was 4:33.79 at the Asian Games in 2010. This leads to an1 f& g, ]: U7 N
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the
, y, I% ]% c2 \7 Jdifference between the gold and silver medal, I see no reason for 5.38 s to
4 u; N8 N+ H' d2 O4 ~* ^7 pbe treated as 7 s.) f. [( e+ _, _" }
& ~" Q4 h; M: o/ \/ t9 Y! DSecond, as previously pointed out, Ye is only 16 years old and her body is* w1 L# j2 k: X
still developing. Bettering oneself by 5 seconds over two years may seem
, t2 Y: H. z2 _1 E/ M$ ]impossible for an adult swimmer, but it certainly happens among youngsters.
0 s% h+ |1 {% X: H' HAn interview with Australian gold medallist Ian Thorpe revealed that his 400
' f; d9 `8 G- m1 ~" C% h; h-metre freestyle time improved by 5 seconds between the ages of 15 and 16.$ d5 \# X: e* Y& s+ s ]6 r
For regular people, including Callaway, it may be hard to imagine what an
" a% I$ s6 H0 |) k/ ?0 ^- Z! @8 `elite swimmer can achieve as he or she matures and undergoes scientific and8 B! D' m* n$ {- @5 m
persistent training. But jumping to the conclusion that it is “anomalous”
2 |( k: P$ K# N! T wbased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.: y6 Y5 q& b. T7 T/ |
" ^8 C, V; \% z9 y& }- n; m2 l* RThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook; R% L. H' V' ~
example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in; Q/ q# x9 A5 N
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so+ Z1 ?0 |' E7 f; y
he chose not to push himself too hard and to conserve his energy for later
# @1 d4 X6 g! E0 s0 zevents (whether this conforms to the Olympic spirit and the ‘use one’s
. c8 h' b& m7 r3 xbest efforts to win a match’ requirement that the Badminton World5 g* w! _3 H0 e3 M0 N' f% R1 C9 ?
Federation recently invoked to disqualify four badminton pairs is another
+ k7 E5 S) E0 s8 g2 H0 Z" h- Y( Stopic worth discussing, though probably not in Nature). Ye, on the other* R1 W/ q" n; {: v' M V
hand, was trailing behind after the first 300 metres and relied on freestyle
1 N* g d! g: V, _1 m5 x# L$ ~+ ^# A8 u, in which she has an edge, to win the race. Failing to mention this
; c/ }* s0 F( Z; w/ a+ e8 qstrategic difference, as well as the fact that Lochte is 23.25 seconds
. Y" s+ s0 B/ @- G0 }2 j G* Mfaster (4:05.18) than Ye overall, creates the illusion that a woman swam
6 d: x: s1 ^6 o' pfaster than the best man in the same sport, which sounds impossible. Putting
4 D" ~* b* G }% R3 Z, Daside the gender argument, I believe this is still a leading question that
5 g- J4 ^$ |* v4 h' G5 Qimplies to the reader that there is something fishy going on.
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Fourth is another example of cherry-picking. In the same event, there are
& N. y; u8 q% B7 \# M/ \! }four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
0 L( n+ F4 o+ \7 ]4 B1 ?5 ms) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s
D5 s" x9 }& h4 B( u5 b3 A), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns6 u. P0 W/ |- o$ Q, ^" _
out, if we are just talking about the last 50 metres in a 400-metre IM,0 |0 s/ h/ R6 B/ V* S
Lochter is not the example I would have used if I were the author. What kind2 Y' D9 J: R) A. [* p- g) }7 M( R
of scientific rigorousness is Callaway trying to demonstrate here? Is it
* h& Y; c- ?! j: Q' C8 o9 dlogical that if Lochter is the champion, we should assume that he leads in
0 s. K" Q2 m' H$ wevery split? That would be a terrible way to teach the public how science
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and- e' \5 U" N. w, E9 q0 T
implies that a drug test cannot rule out the possibility of doping. Is this6 F8 s- H& I. N$ T" C( ~
kind of agnosticism what Nature really wants to teach its readers? By that
1 Z$ c( W+ g9 M+ g) V' t+ tstandard, I estimate that at least half of the peer-reviewed scientific8 n/ a8 W& K8 d7 x
papers in Nature should be retracted. How can one convince the editors and3 R: z' {, e* I* ~( ]( ^; {
reviewers that their proposed theory works for every possible case? One; `, ~9 c: v3 J. g, G6 B
cannot. One chooses to apply the theory to typical examples and to* ] ]' |/ B3 T7 [* n1 n
demonstrate that in (hopefully) all scenarios considered, the theory works
: q: p" E' y/ q. `$ \to a degree, and that that should warrant publication until a counterexample
9 v4 _( D# G5 ~/ G2 ris found. I could imagine that Callaway has a sceptical mind, which is
' t4 I( e2 `, Y1 p/ q" H$ Z* pcrucial to scientific thinking, but that would be put to better use if he; w1 E# l+ |+ C/ _" b
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly Z- w, Q4 h) [$ A3 g8 F% l8 ?1 ^
advanced, non-detectable drug that the Chinese have come up with in the
' a( { w$ Z, E k; }1 [+ C9 Tpast 4 years (they obviously did not have it in Beijing, otherwise why not
" d) n% ^4 j- y5 D, M# iuse it and woo the audience at home?), based on data and rational derivation
( N+ V1 d: y6 W& k3 N0 g. This article, however, can be interpreted as saying that all athletes are
6 k' W( y: w( c5 P9 U" l) G& p. \doping and the authorities are just not good enough to catch them. That may$ ?3 u$ s/ {- |, J3 T
be true, logically, but definitely will not make the case if there is ever a
3 B. K8 x% x! [, ~hearing by the governing body for water sports, FINA, to determine if Ye
# C% t, ]6 b5 C8 I9 V% Jhas doped. To ask whether it is possible to obtain a false negative in a5 Q5 T0 c' O, }# K0 U' r( I& W' c
drug test looks like a rigged question to me. Of course it is possible:8 G; R' v( Z+ I5 T
other than the athlete taking a drug that the test is not designed to detect
/ Y5 v* q* r3 a/ x( {, anyone who has taken quantum 101 will tell you that everything is
9 D6 ^& {/ [' k _- C8 V& dprobabilistic in nature, and so there is a probability that the drug in an
' d6 ?0 \# o' ~5 o) Aathlete’s system could tunnel out right at the moment of the test. A slight
4 r+ I' W3 ?, o+ N. G2 e, Ychance it may be, but should we disregard all test results because of it?) [* Z9 ~2 t; D" i& W8 G+ e* I
Let’s be practical and reasonable, and accept that the World Anti-Doping
D' t+ `4 T' Xagency (WADA) is competent at its job. Ye’s urine sample will be stored for
/ f5 j& q: j5 g- {eight years after the contest for future testing as technology advances.! L; N6 ]" \# U( H& m
Innocent until proven guilty, shouldn’t it be?
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9 K' C2 |% e. c0 ?0 k8 hSixth, and the last point I would like to make, is that the out-of-+ a k: s9 s+ K1 x4 E, `$ ]
competition drug test is already in effect, which Callaway failed to mention
& u4 k. _, ]( x, `, J. As noted in the president of WADA’s press release, drug testing for. q* z: \5 b* Q1 Z+ v/ X& ]. g$ t
Olympians began at least six months before the opening of the London
; F: ]; \! |0 G1 v2 W$ x; [Olympics. Furthermore, 107 athletes have been banned from this Olympics for8 d' i* I9 |) b& I8 g# S
doping. That may be the reason that “everyone will pass at the Olympic
& h' n" `" e4 D& U# B4 ngames. Hardly anyone fails in competition testing” — those who did dope
, y3 y5 F2 X; p$ F1 Ihave already been caught and sanctioned. Callaway is free to suggest that a) Q$ s+ O* L9 c3 q
player could have doped beforehand and fooled the test at the game, but this- w4 C% X, ?: Z; {% ^
possibility is certainly ruled out for Ye.0 @9 P* }6 z7 v3 o2 G. J
3 ?2 P; v+ L3 V* sOver all, even though Callaway did not falsify any data, he did (
+ [( \& ^. Z# x1 |% [intentionally or not) cherry-pick data that, in my view, are far too9 V# @: `: M+ L H5 g
suggestive to be fair and unbiased. If you want to cover a story of a
; r& k$ O+ P* t a% Ssuspected doping from a scientific point of view, be impartial and provide* u; j B* o) u# i* i7 E0 P$ j. y
all the facts for the reader to judge. You are entitled to your
' L* q2 |9 G; w$ N2 Kinterpretation of the facts, and the expression thereof in your piece,
- T) s& v: B' \4 {5 iexplicitly or otherwise, but showing only evidence that favours your; c6 Y* E6 z7 p, r% M6 _5 O
argument is hardly good science or journalism. Such an article in a journal
& G: `& A' K- c" e0 Esuch as Nature is not an appropriate example of how scientific research or9 h m& T. E2 @' V2 o z- O
reporting should be done. |
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