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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
( F+ Y! \8 l& Z/ q; G如果是中国长大的,英语能到这种程度真是很不简单。
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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) Q P% P% Y6 i, VFROM LAI JIANG, Department of Chemistry, University of Pennsylvania
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It is a shame to see Nature — which nearly all scientists, including myself6 B* Z! A0 Q- [ Z" X9 Q
, regard as one of the most prestigious and influential physical-science
f; B7 g" _0 G$ Lmagazines — publish a thinly veiled biased article like this. Granted, this* {3 p/ c# K1 F% y5 |& S/ W
is not a peer-reviewed scientific article and did not go through the
6 J8 h. I- J: { R+ G4 {* Qscrutiny of picking referees. But to serve as a channel for the general) ~3 O* b; @+ |/ O4 E# ]. P
populace to be in touch with and appreciate science, the authors and editors
4 k- @" k# x+ p7 pshould at least present the readers with facts within the proper context,
) K- Z0 f4 a) z! e6 n5 N+ g3 Kwhich they blatantly failed to do.& F7 e( g4 v/ w1 Y7 r; N r
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First, to identify Ye’s performance increase, Ewen Callaway compared her
6 Z% W& {, ~0 U% A; oOlympic 400-metre IM time with her performance at the World Championships in8 ^3 y! X# F& J. n+ ~( P
2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “4 |4 c ^! E$ `+ O) k2 s7 v
anomalous” improvement of around 7 seconds (6.72 s). In fact, her previous
/ M7 j6 h: G Q: u% g# @personal best was 4:33.79 at the Asian Games in 2010. This leads to an* A- R9 X. R9 c
improvement of 5.38 seconds. In a sporting event in which 0.1 s can be the8 R$ P8 C4 z J, P+ i$ B
difference between the gold and silver medal, I see no reason for 5.38 s to
) B! H. |" z+ t( V& R' qbe treated as 7 s.
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Second, as previously pointed out, Ye is only 16 years old and her body is
+ [9 C8 v% {1 V* F& o1 \+ vstill developing. Bettering oneself by 5 seconds over two years may seem
; Y* ]& C, ^/ u6 n- pimpossible for an adult swimmer, but it certainly happens among youngsters.
' k3 K' K# p3 g' [1 j! LAn interview with Australian gold medallist Ian Thorpe revealed that his 4006 J, `% O0 J" Z, F& D9 }7 A
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.: I- p# J6 y9 M: I1 ]1 v; b0 n
For regular people, including Callaway, it may be hard to imagine what an! s4 k1 W% C+ v' ~* z
elite swimmer can achieve as he or she matures and undergoes scientific and( t+ m4 }, ]7 F' T% q9 o, }5 s
persistent training. But jumping to the conclusion that it is “anomalous”
1 b6 g( o `" P8 kbased on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.
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$ o2 @- g& D6 y, E U) IThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
# |1 H" S( S# }example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in$ {; S7 f- c) O$ @
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so& V- a! S+ |% R, L* { {# M5 U
he chose not to push himself too hard and to conserve his energy for later. d; S$ Q: s# ~: g, w8 ?5 b
events (whether this conforms to the Olympic spirit and the ‘use one’s
# D4 L, ^9 [6 o8 z _. S2 Xbest efforts to win a match’ requirement that the Badminton World
+ d! v: _& I2 r6 J9 z nFederation recently invoked to disqualify four badminton pairs is another
3 x# h2 i7 O6 H. Utopic worth discussing, though probably not in Nature). Ye, on the other
7 |- c; s6 | }& V( p( {hand, was trailing behind after the first 300 metres and relied on freestyle
1 |* {% m$ M+ ?( i, v5 S- y, in which she has an edge, to win the race. Failing to mention this
9 \% V* Y- N( K9 Y& sstrategic difference, as well as the fact that Lochte is 23.25 seconds
% L& {. ?' H q( Vfaster (4:05.18) than Ye overall, creates the illusion that a woman swam
% A3 k/ c$ ~/ W' \0 ]7 s, lfaster than the best man in the same sport, which sounds impossible. Putting
" S+ ?, L$ y: o/ @7 Zaside the gender argument, I believe this is still a leading question that/ W3 n5 h0 w2 j$ w& r! C
implies to the reader that there is something fishy going on. u4 C6 s# t6 }% @0 K( D9 H
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Fourth is another example of cherry-picking. In the same event, there are/ r5 z/ v/ L$ ^. H
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
- L$ Y( K% _0 A2 x7 }: Ks) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s9 L& C! ]: s& y9 }
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
3 b# u! y |1 c* s* Y/ l% M9 J6 I1 h2 sout, if we are just talking about the last 50 metres in a 400-metre IM,
1 B1 M$ l( b7 t! S2 W0 _+ e" oLochter is not the example I would have used if I were the author. What kind3 v% _" b9 g& L: O( s {/ A
of scientific rigorousness is Callaway trying to demonstrate here? Is it
1 q' h9 I6 K) U/ Wlogical that if Lochter is the champion, we should assume that he leads in
8 Q e% _! s; L: F0 B3 G1 U8 tevery split? That would be a terrible way to teach the public how science
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( g3 v0 E$ I# F) RFifth is the issue I oppose the most. Callaway quotes Ross Tucker and9 o5 w* F3 } I& e# o) ?, y
implies that a drug test cannot rule out the possibility of doping. Is this8 n- ~- C/ g, s+ G" K
kind of agnosticism what Nature really wants to teach its readers? By that& h" B4 t1 M7 L
standard, I estimate that at least half of the peer-reviewed scientific3 s+ V) [+ B4 l/ q8 Q
papers in Nature should be retracted. How can one convince the editors and
/ L2 D5 u5 _6 x2 Y' h! G& N7 s# {; s" yreviewers that their proposed theory works for every possible case? One9 Z. B, X8 k' x! J2 i
cannot. One chooses to apply the theory to typical examples and to& g! i: R1 d% `4 V+ b
demonstrate that in (hopefully) all scenarios considered, the theory works7 N8 O5 {) b9 z+ g" ]3 b6 Q
to a degree, and that that should warrant publication until a counterexample; }! D1 K2 e( L0 @
is found. I could imagine that Callaway has a sceptical mind, which is
' F/ P2 I/ b0 f: ^! H, Ycrucial to scientific thinking, but that would be put to better use if he' |3 H$ @, a2 Y% ?9 r) U3 f# |8 `
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly, ~9 ^) q4 a6 c/ T
advanced, non-detectable drug that the Chinese have come up with in the5 l+ ~$ H1 C8 c2 N. z7 c0 z
past 4 years (they obviously did not have it in Beijing, otherwise why not. O. a: ^+ N; s: ^' `$ `. S* X7 S- s
use it and woo the audience at home?), based on data and rational derivation
" s2 y. W, d4 y( _9 a. b. This article, however, can be interpreted as saying that all athletes are
. R' f0 V, @2 I; V8 z% `doping and the authorities are just not good enough to catch them. That may5 r/ A& k x8 I
be true, logically, but definitely will not make the case if there is ever a
2 A4 Y! C1 e8 I* _% S; d' U' Vhearing by the governing body for water sports, FINA, to determine if Ye
" p# m0 @( P3 C: K9 u" C* lhas doped. To ask whether it is possible to obtain a false negative in a
8 B) J8 a, V2 @* g+ Q6 xdrug test looks like a rigged question to me. Of course it is possible:. \1 c/ V% @' \
other than the athlete taking a drug that the test is not designed to detect
: \0 H$ H- @8 @7 [9 v6 Y, anyone who has taken quantum 101 will tell you that everything is# `; H7 E+ S4 M, }+ e
probabilistic in nature, and so there is a probability that the drug in an
7 r( N4 o2 m) Z% v1 t4 o! T$ _% Mathlete’s system could tunnel out right at the moment of the test. A slight2 Z6 C9 D/ w! W8 u5 J& Z a
chance it may be, but should we disregard all test results because of it?
- Y2 t5 a# }% T7 d5 x6 [6 z. PLet’s be practical and reasonable, and accept that the World Anti-Doping
Q5 B/ h$ b+ Vagency (WADA) is competent at its job. Ye’s urine sample will be stored for
; e# b( B: k z4 `eight years after the contest for future testing as technology advances.+ b6 P8 J1 w! }2 s! i( q
Innocent until proven guilty, shouldn’t it be?
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U# m8 @, h* `0 }# g4 R( ESixth, and the last point I would like to make, is that the out-of-
b! q0 C* v! C5 Tcompetition drug test is already in effect, which Callaway failed to mention
( l+ ^/ Q& |+ x9 ~/ v. As noted in the president of WADA’s press release, drug testing for: W6 e) {0 T2 J9 K
Olympians began at least six months before the opening of the London1 B( U/ d7 ?, w# A3 d1 Y2 z
Olympics. Furthermore, 107 athletes have been banned from this Olympics for2 F1 U, T2 s$ Y$ a% A' U
doping. That may be the reason that “everyone will pass at the Olympic. E; n9 K- d2 k9 Y5 B! ~9 V7 d
games. Hardly anyone fails in competition testing” — those who did dope' o6 d' t5 a- o1 _: `" N
have already been caught and sanctioned. Callaway is free to suggest that a5 O8 _! J! f4 s7 e7 M, K* {- r
player could have doped beforehand and fooled the test at the game, but this; }6 D9 K3 G* C& m3 l0 Q# h
possibility is certainly ruled out for Ye.
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Over all, even though Callaway did not falsify any data, he did () ]5 @7 d. W7 f r- N: _
intentionally or not) cherry-pick data that, in my view, are far too
3 J% U P! t% `) F5 a: L" P2 lsuggestive to be fair and unbiased. If you want to cover a story of a- Z, I+ x# ^/ g, n
suspected doping from a scientific point of view, be impartial and provide! F" t! V9 G3 }% X
all the facts for the reader to judge. You are entitled to your
# j g7 M9 x" v; z) R* o, \6 ointerpretation of the facts, and the expression thereof in your piece,2 r* k! [ E) {1 z& S, ?
explicitly or otherwise, but showing only evidence that favours your- W: G6 d: R" J6 T6 a4 d2 p
argument is hardly good science or journalism. Such an article in a journal4 ]! W1 [- S6 v- E0 \
such as Nature is not an appropriate example of how scientific research or
. M, R, ^* Y0 j1 j! T' freporting should be done. |
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